| Type | Description |
|---|---|
| Definition | REC8 meiotic recombination protein |
| Date | Results | Publications |
|---|---|---|
| 2017-11-18 10:42:00 | Our genetic analysis demonstrates that cohesins containing STAG3 and REC8 are the main complex required for centromeric cohesion, and RAD21L cohesins are required for normal clustering of pericentromeric heterochromatin. Furthermore, the STAG3/REC8 and STAG3/RAD21L cohesins are the primary cohesins required for axis formation. | 27172213 |
| 2017-08-19 12:38:00 | REC8-containing cohesin complexes provide canonical SCC, not RAD21 or RAD21L, at the prophase stage of meiosis I in spermatocytes. | 27170622 |
| 2017-04-29 10:06:00 | To decipher the functions of the two meiosis-specific kleisins, REC8 or RAD21L, together with the only meiosis-specific SMC protein SMC1b, we generated Smc1b-/-Rec8-/- and Smc1b-/-Rad21L-/- mouse mutants. | 27792785 |
| 2017-01-14 10:44:00 | Rec8 establishes cohesion when activated during DNA replication in fetal oocytes using tamoxifen-inducible Cre. In contrast, no new cohesion is detected when Rec8 is activated in arrested oocytes by tamoxifen despite cohesin synthesis. | 26898469 |
| 2016-09-17 10:47:00 | Plk1 activity is required for meiotic spindle assembly and REC8 cleavage, with pPlk1Ser137 being the action executor, in mouse oocytes during meiotic division. | 26654596 |
| Type | IDs |
|---|---|
| Synonymous | Rec8L1, mrec |
| Gene |
UniProtKB-ID:
REC8_MOUSE
UniprotKB:
Q8C5S7
UniParc:
UPI0000020C40
EMBL:
AF262055,
BC052155,
AK077167,
AK146832
Ensembl:
ENSMUSG00000002324
KO:
mmu:56739
|
| Nucleutide sequences |
EMBL-CDS:
AAH52155.1,
BAC36657.1,
AAF69524.1,
BAE27467.1
Ensembl_TRS:
ENSMUST00000002395
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002395
RefSeq:
NP_001347319.1,
NP_001347318.1,
NP_064386.2
|
| Others |
UniRef100:
UniRef100_Q8C5S7
UniRef90:
UniRef90_Q8C5S7
UniRef50:
UniRef50_Q8C5S7
UniGene:
Mm.23149
CCDS:
CCDS27120.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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