| Type | Description |
|---|---|
| Definition | SLC2A4 regulator |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:21:00 | KRAS K104 modification affects the KRAS(G12D)-GEF interaction and mediates cell growth and motility. | 33060649 |
| 2019-06-29 11:16:00 | our results demonstrate that nuclear SLC2A4RG induces cell apoptosis in a new manner via direct transactivation of caspase-3 caspase-6 in glioma, but the interaction with 14-3-3theta; will result in sequestration of SLC2A4RG in the cytoplasm and then promote tumor progression. | 30686753 |
| 2010-01-21 00:00:00 | GEF and MEF2A have roles in regulating the GLUT4 promoter | 14630949 |
| 2010-01-21 00:00:00 | HDBP1 and HDBP2 are novel transcription factors shuttling between nucleus and cytoplasm and bind to the specific GCCGGCG, which is an essential cis-element for HD gene expression in neuronal cells | 14625278 |
| 2010-01-21 00:00:00 | Exercise increases MEF2 and GEF DNA binding and imply that these transcription factors could be potential targets for modulating GLUT4 expression in human skeletal muscle. | 16368714 |
| Type | IDs |
|---|---|
| Synonymous | GEF, HDBP-1, HDBP1, Si-1-2, Si-1-2-19 |
| Gene |
UniProtKB-ID:
S2A4R_HUMAN
UniprotKB:
Q9NR83
UniParc:
UPI00024CD4A6,
UPI000013D6CE,
UPI0000420B12
EMBL:
AB052777,
AB044786,
BC028349,
BC052306,
AB044777,
AF249267,
BC017446,
AL121845,
BC001402
Ensembl:
ENSG00000125520
KO:
hsa:56731
|
| Nucleutide sequences |
EMBL-CDS:
BAE71373.1,
AAH52306.1,
AAH28349.2,
AAH01402.2,
AAF97516.2,
BAD29732.1,
BAD29733.1,
AAH17446.1
Ensembl_TRS:
ENST00000266077
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000266077
RefSeq:
NP_064446.2
|
| Others |
UniRef100:
UniRef100_Q9NR83
UniRef90:
UniRef90_Q9NR83
UniRef50:
UniRef50_Q9NR83
UniGene:
Hs.435126
CCDS:
CCDS13537.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33060649 |
KRAS K104 modification affects the KRASG12D-GEF interaction and mediates cell growth and motility. Sci Rep Chih-Chieh Chen , Chia-Yi Hsu , Hsiao-Yun Lin , Hong-Qi Zeng , Kuang-Hung Cheng , Chia-Wei Wu , Eing-Mei Tsai , Tsung-Hua Hsieh |
2020-10-15 | - |
| 30686753 |
EBioMedicine Dapeng Yun , Hongxiang Wang , Yuqi Wang , Yuanyuan Chen , Zhipeng Zhao , Jiawei Ma , Yuanyuan Ji , Qilin Huang , Juxiang Chen , Hongyan Chen , Daru Lu |
2019-02-01 | - |
| 28986522 |
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism. Nat Commun Giulia Antoniali , Fabrizio Serra , Lisa Lirussi , Mikiei Tanaka , Chiara D'Ambrosio , Shiheng Zhang , Slobodanka Radovic , Emiliano Dalla , Yari Ciani , Andrea Scaloni , Mengxia Li , Silvano Piazza , Gianluca Tell |
2017-10-06 | - |
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 23128233 |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature Luke Jostins , Stephan Ripke , Rinse K Weersma , Richard H Duerr , Dermot P McGovern , Ken Y Hui , James C Lee , L Philip Schumm , Yashoda Sharma , Carl A Anderson , Jonah Essers , Mitja Mitrovic , Kaida Ning , Isabelle Cleynen , Emilie Theatre , Sarah L Spain , Soumya Raychaudhuri , Philippe Goyette , Zhi Wei , Clara Abraham , Jean-Paul Achkar , Tariq Ahmad , Leila Amininejad , Ashwin N Ananthakrishnan , Vibeke Andersen , Jane M Andrews , Leonard Baidoo , Tobias Balschun , Peter A Bampton , Alain Bitton , Gabrielle Boucher , Stephan Brand , Carsten Büning , Ariella Cohain , Sven Cichon , Mauro D'Amato , Dirk De Jong , Kathy L Devaney , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Lynnette R Ferguson , Denis Franchimont , Karin Fransen , Richard Gearry , Michel Georges , Christian Gieger , Jürgen Glas , Talin Haritunians , Ailsa Hart , Chris Hawkey , Matija Hedl , Xinli Hu , Tom H Karlsen , Limas Kupcinskas , Subra Kugathasan , Anna Latiano , Debby Laukens , Ian C Lawrance , Charlie W Lees , Edouard Louis , Gillian Mahy , John Mansfield , Angharad R Morgan , Craig Mowat , William Newman , Orazio Palmieri , Cyriel Y Ponsioen , Uros Potocnik , Natalie J Prescott , Miguel Regueiro , Jerome I Rotter , Richard K Russell , Jeremy D Sanderson , Miquel Sans , Jack Satsangi , Stefan Schreiber , Lisa A Simms , Jurgita Sventoraityte , Stephan R Targan , Kent D Taylor , Mark Tremelling , Hein W Verspaget , Martine De Vos , Cisca Wijmenga , David C Wilson , Juliane Winkelmann , Ramnik J Xavier , Sebastian Zeissig , Bin Zhang , Clarence K Zhang , Hongyu Zhao , International IBD Genetics Consortium (IIBDGC) , Mark S Silverberg , Vito Annese , Hakon Hakonarson , Steven R Brant , Graham Radford-Smith , Christopher G Mathew , John D Rioux , Eric E Schadt , Mark J Daly , Andre Franke , Miles Parkes , Severine Vermeire , Jeffrey C Barrett , Judy H Cho |
2012-11-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21297633 |
Nat. Genet. Carl A Anderson , Gabrielle Boucher , Charlie W Lees , Andre Franke , Mauro D'Amato , Kent D Taylor , James C Lee , Philippe Goyette , Marcin Imielinski , Anna Latiano , Caroline Lagacé , Regan Scott , Leila Amininejad , Suzannah Bumpstead , Leonard Baidoo , Robert N Baldassano , Murray Barclay , Theodore M Bayless , Stephan Brand , Carsten Büning , Jean-Frédéric Colombel , Lee A Denson , Martine De Vos , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Rudolf S N Fehrmann , James A B Floyd , Timothy Florin , Denis Franchimont , Lude Franke , Michel Georges , Jürgen Glas , Nicole L Glazer , Stephen L Guthery , Talin Haritunians , Nicholas K Hayward , Jean-Pierre Hugot , Gilles Jobin , Debby Laukens , Ian Lawrance , Marc Lémann , Arie Levine , Cecile Libioulle , Edouard Louis , Dermot P McGovern , Monica Milla , Grant W Montgomery , Katherine I Morley , Craig Mowat , Aylwin Ng , William Newman , Roel A Ophoff , Laura Papi , Orazio Palmieri , Laurent Peyrin-Biroulet , Julián Panés , Anne Phillips , Natalie J Prescott , Deborah D Proctor , Rebecca Roberts , Richard Russell , Paul Rutgeerts , Jeremy Sanderson , Miquel Sans , Philip Schumm , Frank Seibold , Yashoda Sharma , Lisa A Simms , Mark Seielstad , A Hillary Steinhart , Stephan R Targan , Leonard H van den Berg , Morten Vatn , Hein Verspaget , Thomas Walters , Cisca Wijmenga , David C Wilson , Harm-Jan Westra , Ramnik J Xavier , Zhen Z Zhao , Cyriel Y Ponsioen , Vibeke Andersen , Leif Torkvist , Maria Gazouli , Nicholas P Anagnou , Tom H Karlsen , Limas Kupcinskas , Jurgita Sventoraityte , John C Mansfield , Subra Kugathasan , Mark S Silverberg , Jonas Halfvarson , Jerome I Rotter , Christopher G Mathew , Anne M Griffiths , Richard Gearry , Tariq Ahmad , Steven R Brant , Mathias Chamaillard , Jack Satsangi , Judy H Cho , Stefan Schreiber , Mark J Daly , Jeffrey C Barrett , Miles Parkes , Vito Annese , Hakon Hakonarson , Graham Radford-Smith , Richard H Duerr , Séverine Vermeire , Rinse K Weersma , John D Rioux |
2011-03-01 | - |
| 21102463 |
Nat. Genet. Andre Franke , Dermot P B McGovern , Jeffrey C Barrett , Kai Wang , Graham L Radford-Smith , Tariq Ahmad , Charlie W Lees , Tobias Balschun , James Lee , Rebecca Roberts , Carl A Anderson , Joshua C Bis , Suzanne Bumpstead , David Ellinghaus , Eleonora M Festen , Michel Georges , Todd Green , Talin Haritunians , Luke Jostins , Anna Latiano , Christopher G Mathew , Grant W Montgomery , Natalie J Prescott , Soumya Raychaudhuri , Jerome I Rotter , Philip Schumm , Yashoda Sharma , Lisa A Simms , Kent D Taylor , David Whiteman , Cisca Wijmenga , Robert N Baldassano , Murray Barclay , Theodore M Bayless , Stephan Brand , Carsten Büning , Albert Cohen , Jean-Frederick Colombel , Mario Cottone , Laura Stronati , Ted Denson , Martine De Vos , Renata D'Inca , Marla Dubinsky , Cathryn Edwards , Tim Florin , Denis Franchimont , Richard Gearry , Jürgen Glas , Andre Van Gossum , Stephen L Guthery , Jonas Halfvarson , Hein W Verspaget , Jean-Pierre Hugot , Amir Karban , Debby Laukens , Ian Lawrance , Marc Lemann , Arie Levine , Cecile Libioulle , Edouard Louis , Craig Mowat , William Newman , Julián Panés , Anne Phillips , Deborah D Proctor , Miguel Regueiro , Richard Russell , Paul Rutgeerts , Jeremy Sanderson , Miquel Sans , Frank Seibold , A Hillary Steinhart , Pieter C F Stokkers , Leif Torkvist , Gerd Kullak-Ublick , David Wilson , Thomas Walters , Stephan R Targan , Steven R Brant , John D Rioux , Mauro D'Amato , Rinse K Weersma , Subra Kugathasan , Anne M Griffiths , John C Mansfield , Severine Vermeire , Richard H Duerr , Mark S Silverberg , Jack Satsangi , Stefan Schreiber , Judy H Cho , Vito Annese , Hakon Hakonarson , Mark J Daly , Miles Parkes |
2010-12-01 | - |
| 18249389 |
Fertil. Steril. Michelle R Jones , Scott G Wilson , Ben H Mullin , Robert Mead , Frank Dudbridge , Gerald F Watts , Bronwyn G A Stuckey |
2008-12-01 |
INSR,
MEF2A,
PIK3R1,
SLC2A4RG,
SLC2A4
|
| 18216015 |
J Biol Chem David P Sparling , Beth A Griesel , Juston Weems , Ann Louise Olson |
2008-03-21 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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