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5673 PSG5

5673

PSG5

pregnancy specific beta-1-glycoprotein 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition pregnancy specific beta-1-glycoprotein 5

研究结论

Date Results Publications
2013-09-14 12:12:00 show that human PSG1 binds alphaIIbbeta3 and inhibits the platelet - fibrinogen interaction. Unexpectedly, however, the KGD is not critical as multiple PSG1 domains independently bind and inhibit alphaIIbbeta3 function 23469002
2013-08-10 11:47:00 esults are consistent with a regulatory role of lysine acetylation on PSG expression through a relaxed chromatin state and an increase in the transcriptional activity of Sp1 and KLF6 following an augmented Sp1 acetylation and KLF6 nuclear localization. 23418492
2010-01-21 00:00:00 the mRNA expression of PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN is up-regulated in cells circulating within blood from women with preeclampsia, and is positively correlated with cliical severity 17978129
2010-01-21 00:00:00 Strong synergic activity of KLF4 and Sp1 on the PSG-5 promoter. 16563348

名称对应

Type IDs
Synonymous FL-NCA-3, PSG
Gene
UniProtKB-ID: PSG5_HUMAN, A0A024R0S1_HUMAN
UniprotKB: Q15238, A0A024R0S1
UniParc: UPI000013C7B9
EMBL: BC012607, CH471126, AC005392, M25384, M73713, AH007626
Ensembl: ENSG00000204941
KO: hsa:5673
Nucleutide sequences
EMBL-CDS: AAA60205.1, AAH12607.1, AAA36514.1, AAD28500.1, EAW57173.1, EAW57171.1, EAW57172.1
Gene_ORFName: hCG_1995683
Ensembl_TRS: ENST00000342951, ENST00000407356, ENST00000366175
Protein sequencees
Ensembl_PRO: ENSP00000386008, ENSP00000344413, ENSP00000382334
RefSeq: NP_001123486.1, XP_011525434.1, NP_002772.3, XP_016882492.1
Others
UniRef100: UniRef100_Q15238
UniRef90: UniRef90_Q15238
UniRef50: UniRef50_Q00888-2
UniGene: Hs.654415
CCDS: CCDS12617.1

全选

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研究热度

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