| Type | Description |
|---|---|
| Definition | LPS-induced TN factor |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:09:00 | results indicate that SIMPLE may regulate protein trafficking physiologically by localizing to the TGN and/or REs by binding PI4P. | 29953492 |
| 2016-10-01 11:55:00 | Suggest LITAF as regulatory of pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease. | 26573228 |
| 2015-09-26 12:34:00 | Data suggest that atypical inflammatory signaling kinetics may account for the gain of function elicited by the Litaf protein SIMPLE mutation in Charcot-Marie-Tooth Type 1C (CMT1C) patients. | 25963657 |
| 2013-12-21 10:48:00 | Mutation of SIMPLE (Litaf) in Charcot-Marie-Tooth 1C alters production of exosomes. | 23576546 |
| 2013-01-26 10:49:00 | This study demonistrated that loss of Litaf function is unlikely to be a major contributor to Charcot-Marie-Tooth disease, but modulating effects of macrophages need to be considered in the etiology of the disease. | 22729949 |
| Type | IDs |
|---|---|
| Synonymous | 3222402J11Rik, C85531, N4WBP3, TBX1 |
| Gene |
UniProtKB-ID:
LITAF_MOUSE
UniprotKB:
Q9JLJ0
UniParc:
UPI0000002EEB
EMBL:
BC018559,
AK151053,
AF230522,
AK076162,
AK159533,
AF171100,
AF220207,
AK018578
Ensembl:
ENSMUSG00000022500
KO:
mmu:56722
|
| Nucleutide sequences |
EMBL-CDS:
BAE35161.1,
BAB31289.1,
AAF27312.1,
AAH18559.1,
BAE30070.1,
AAG44246.1,
BAC36228.1,
AAO49168.1
Ensembl_TRS:
ENSMUST00000117360,
ENSMUST00000023143
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023143,
ENSMUSP00000112667
RefSeq:
NP_064364.1,
XP_030105082.1
|
| Others |
UniRef100:
UniRef100_Q9JLJ0
UniRef90:
UniRef90_Q9JLJ0
UniRef50:
UniRef50_Q99732
UniGene:
Mm.294753
CCDS:
CCDS27958.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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