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56695 Pnkd

56695

Pnkd

paroxysmal nonkinesiogenic dyskinesia

protein-coding

Mus musculus

基因描述

Type Description
Definition paroxysmal nonkinesiogenic dyskinesia

研究结论

Date Results Publications
2015-05-16 12:55:00 PNKD KO mice, RIM1/2 protein levels are reduced and synaptic strength is impaired. Thus, PNKD is a novel synaptic protein with a regulatory role in neurotransmitter release 25730884
2012-04-21 12:01:00 These findings support the hypothesis that the PNKD protein functions to modulate striatal neuro-transmitter release in response to stress and other precipitating factors. 22214848
2010-03-01 11:13:00 these findings suggest that silencing MR-1 protected mice myocardium against inflammatory injury induced by AngII by suppression of pro-inflammatory transcription factors NF-kappaB and AP-1 signaling pathway. 20040360
2010-01-21 00:00:00 MR-1 plays an aggravative role in the development of cardiac hypertrophy via activation of the nuclear factor kappaB signaling pathway 17420335
2007-06-15 11:07:00 Paroxysmal non-kinesigenic dyskinesia (PNKD) is characterized by spontaneous hyperkinetic attacks that are precipitated by alcohol, coffee, stress and fatigue. 15496428

名称对应

Type IDs
Synonymous 2210013N15Rik, 2810403H05Rik, AI854243, Brp17, MNCb-5687, MR-1, Tahccp2
Gene
UniProtKB-ID: PNKD_MOUSE, A0A0R4J1J1_MOUSE
UniprotKB: Q69ZP3, A0A0R4J1J1
UniParc: UPI0000022812, UPI00015B3BEF, UPI0000071AEC, UPI00001D9479, UPI00006976B2
EMBL: AK166548, BC116237, AC113473, AB041609, BC116236, AY299972, AY039041, BC008274, AY039042, AK012976, AK009545, BC058945, AF318058, AK173125, AK041238, AC098570
Ensembl: ENSMUSG00000026179
KO: mmu:56695
Nucleutide sequences
EMBL-CDS: AAP58373.1, AAH08274.1, AAI16238.1, BAB26351.1, AAH58945.1, AAL25717.1, BAA95092.1, AAI16237.1, AAK83448.1, BAC30873.1, AAK83447.1, BAB28577.2, BAD32403.1, BAE38846.1
Gene_ORFName: MNCb-5687, Fksg19
Ensembl_TRS: ENSMUST00000087225, ENSMUST00000087226, ENSMUST00000027370, ENSMUST00000113805
Protein sequencees
Ensembl_PRO: ENSMUSP00000027370, ENSMUSP00000084477, ENSMUSP00000084478, ENSMUSP00000109436
RefSeq: XP_006496230.1, NP_079856.2, NP_001034598.1, NP_064383.1
Others
UniRef100: UniRef100_Q69ZP3, UniRef100_Q96P23
UniRef90: UniRef90_M0RBK9, UniRef90_Q8N490
UniRef50: UniRef50_Q8N490, UniRef50_Q69ZP3-2
UniGene: Mm.384726
CCDS: CCDS35613.1, CCDS15045.1, CCDS35614.1

全选

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