| Type | Description |
|---|---|
| Definition | malonyl-CoA decarboxylase |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 12:44:00 | Decreased fat oxidation in MCD(-/-) mice resulted in the accumulation of lipid intermediates in peripheral tissues, but this was not associated with a worsening of age-associated insulin resistance and, conversely, improved longevity. | 27207536 |
| 2015-05-23 10:41:00 | MCD(-/-) mice consistently exhibited cardiac dysfunction and severe metabolic perturbations while on a high-fat, low carbohydrate diet of maternal milk and these gradually resolved post-weaning. | 25066696 |
| 2014-10-04 10:58:00 | Data indicate that a full-dosage of p53 and an intact ribosomal protein-murine double minute 2 protein (Mdm2)-p53 pathway are required for the induction of malonyl coA decarboxylase (MCD), a critical regulator of fatty acid oxidation. | 24872453 |
| 2013-08-31 10:16:00 | SIRT4 deacetylates and represses malonyl CoA decarboxylase, regulating malonyl coA levels. | 23746352 |
| 2010-11-27 10:09:00 | This study of fatty acid oxidation and malonyl-CoA decarboxylase identifies a critical role for metabolism in both the normal pulmonary circulation (hypoxic pulmonary vasoconstriction) and pulmonary hypertension | 20702857 |
| Type | IDs |
|---|---|
| Synonymous | AI324784, Mcd |
| Gene |
UniProtKB-ID:
DCMC_MOUSE
UniprotKB:
Q99J39
UniParc:
UPI0000D7A48A,
UPI0000026C5C
EMBL:
AY331094,
AK082479,
BC004764
Ensembl:
ENSMUSG00000074064
KO:
mmu:56690
|
| Nucleutide sequences |
EMBL-CDS:
AAH04764.1,
AAP93335.2,
BAC38505.1
Ensembl_TRS:
ENSMUST00000098367
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095970
RefSeq:
NP_064350.2,
XP_006531285.1,
XP_017168411.1,
XP_006531288.1,
XP_011246759.1,
NP_001351257.1,
XP_006531289.1,
XP_006531281.1
|
| Others |
UniRef100:
UniRef100_Q99J39
UniRef90:
UniRef90_Q920F5
UniRef50:
UniRef50_Q920F5
UniGene:
Mm.423037
CCDS:
CCDS22703.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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