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5669 PSG1

5669

PSG1

pregnancy specific beta-1-glycoprotein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition pregnancy specific beta-1-glycoprotein 1

研究结论

Date Results Publications
2019-04-27 12:03:00 biomarkers suitable for the assessment of chronological ageing were identified, and extrapolated to the context of photo-damaged skin. In particular, KANK4, ACAN, Col XI alpha1, and PSG1, were expressed at an increased level in both chronologically-aged and photo-damaged skin. 29913199
2017-07-01 10:36:00 Inhibiting PSG1 can effectively reduce chemoresistance via a transforming growth factor-beta (TGF-beta)-related pathway in ER-negative breast cancer cells. 27653744
2017-02-18 10:53:00 PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma. 27595833
2017-01-28 10:23:00 Under conditions of directed induction of phenotypic changes in CD4(+) lymphocytes to regulatory T cells (Treg), pregnancy-specific at high concentrations (10 and 100 mug/mL) increased FOXP3 expression. The evaluation of the spontaneous expression level of FOXP3 mRNA showed that pregnancy-specific beta1-glycoprotein (1 and 100 mug/mL) stimulated the expression of this factor in mononuclear cells and isolated CD4(+) lym... 27817017
2016-12-17 12:10:00 results identify a non-placental site of PSG expression in the gut and associated tumors, with implications for determining whether PSGs have a role in tumor progression, and utility as tumor biomarkers. 26926266

名称对应

Type IDs
Synonymous B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1
Gene
UniProtKB-ID: PSG1_HUMAN, O75238_HUMAN, G5E9F7_HUMAN
UniprotKB: P11464, O75238, G5E9F7
UniParc: UPI000002B1BC, UPI0000001071, UPI000006E746, UPI000013279D, UPI000049DEBA, UPI000006DB43
EMBL: M17909, M33663, M20879, BC022338, M25385, CH471126, M21822, J04539, AH007517, M34715, M33664, M20881, AC005238, M17908, BC058285, M37397, CR450329
Ensembl: ENSG00000231924
KO: hsa:5669
Nucleutide sequences
EMBL-CDS: AAA52601.1, AAH22338.1, AAA36513.1, CAG29325.1, AAC25488.1, AAH58285.1, AAD21020.1, AAA52602.1, AAC25490.1, EAW57156.1, AAC25489.1, AAA52591.1, AAA60960.1, AAA52603.1, AAA36511.1, AAA36517.1, AAA60204.1, AAA36515.1, AAA52590.1, AAC25484.1, EAW57161.1, EAW57154.1
Gene_ORFName: hCG_1995688, hCG_1995688
Ensembl_TRS: ENST00000244296, ENST00000312439, ENST00000436291, ENST00000595356, ENST00000403380
Protein sequencees
Ensembl_PRO: ENSP00000472610, ENSP00000413041, ENSP00000244296, ENSP00000308970, ENSP00000385386
RefSeq: NP_001171755.1, NP_008836.2, NP_001171754.1, NP_001284702.1, NP_001317453.1, XP_005259122.1, XP_011525427.1
Others
UniRef100: UniRef100_G5E9F7, UniRef100_P11464, UniRef100_O75238
UniRef90: UniRef90_O75238, UniRef90_P11464, UniRef90_G5E9F7
UniRef50: UniRef50_Q00888-2, UniRef50_P11464
UniGene: Hs.709192
CCDS: CCDS74380.1, CCDS54275.1, CCDS12612.1, CCDS59392.1

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