| Type | Description |
|---|---|
| Definition | UPF3A regulator of nonsense mediated mRNA decay |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:51:00 | mRNA bearing a premature termination codon (PTC) promptly triggers a genetic compensation response (GCR)that involves Upf3a and components of the COMPASS complex; findings provide a potential mechanistic basis for the GCR, and may help lead to the development of therapeutic strategies that treat missense mutations associated with genetic disorders | 30944473 |
| Type | IDs |
|---|---|
| Synonymous | si:dkey-21o13.6 |
| Gene |
UniProtKB-ID:
REN3A_DANRE
UniprotKB:
B0S733
UniParc:
UPI000175FE0A,
UPI0000F1EF73
EMBL:
BC095761,
BX601644
Ensembl:
ENSDARG00000069297,
ENSDARG00000111067
KO:
dre:566608
|
| Nucleutide sequences |
EMBL-CDS:
CAQ15001.1,
AAH95761.1
Gene_ORFName:
si:dkey-21o13.6
Ensembl_TRS:
ENSDART00000139608,
ENSDART00000100728,
ENSDART00000123005
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000114416,
ENSDARP00000105134,
ENSDARP00000091501
RefSeq:
NP_001189377.1,
XP_017213192.1,
XP_005167908.1,
XP_005167907.1
|
| Others |
UniRef100:
UniRef100_B0S733
UniRef90:
UniRef90_B0S733
UniRef50:
UniRef50_Q9H1J1
UniGene:
Dr.91982
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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