| Type | Description |
|---|---|
| Definition | potassium two pore domain channel subfamily K member 12 |
| Date | Results | Publications |
|---|---|---|
| 2015-02-07 10:06:00 | In cell and tissues co-expressing THIK1 and THIK2, heterodimeric channels may contribute to cell excitability. | 25148687 |
| 2014-02-15 10:39:00 | The cytoplasmic amino-terminal region of THIK2 (Nt-THIK2) contains an arginine-rich motif (RRSRRR) that acts as a retention/retrieval signal. | 24163367 |
| 2010-01-21 00:00:00 | THIK-1 and THIK-2 are abundantly expressed in the proximal and distal nephron of the mammalian kidney. | 18209473 |
| 2008-08-13 21:30:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 18676988 |
| Type | IDs |
|---|---|
| Synonymous | K2p12.1, THIK-2, THIK2 |
| Gene |
UniProtKB-ID:
KCNKC_HUMAN
UniprotKB:
Q9HB15
UniParc:
UPI000000DC4C
EMBL:
BC047749,
AF287302
Ensembl:
ENSG00000184261
KO:
hsa:56660
|
| Nucleutide sequences |
EMBL-CDS:
AAH47749.1,
AAG32313.1
Ensembl_TRS:
ENST00000327876
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327611
RefSeq:
NP_071338.1
|
| Others |
UniRef100:
UniRef100_Q9HB15
UniRef90:
UniRef90_Q9ERS1
UniRef50:
UniRef50_Q9ERS1
UniGene:
Hs.591586
CCDS:
CCDS1835.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 25148687 |
J Biol Chem Sandy Blin , Franck C Chatelain , Sylvain Feliciangeli , Dawon Kang , Florian Lesage , Delphine Bichet |
2014-10-10 | - |
| 24412244 |
Charting the molecular links between driver and susceptibility genes in colorectal cancer. Biochem. Biophys. Res. Commun. Rodrigo Arroyo , Miquel Duran-Frigola , Clara Berenguer , Montserrat Soler-López , Patrick Aloy |
2014-03-21 |
DLC1,
ERBB2,
AKT1,
SMAD1,
SMAD4,
PTPN12,
RASA1,
SHC1,
BCL10
|
| 24163367 |
J Biol Chem Franck C Chatelain , Delphine Bichet , Sylvain Feliciangeli , Marie-Madeleine Larroque , Véronique M Braud , Dominique Douguet , Florian Lesage |
2013-12-06 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19890347 |
J. Invest. Dermatol. Stanca A Birlea , Katherine Gowan , Pamela R Fain , Richard A Spritz |
2010-03-01 |
HUNK,
IDDM8,
ATP8B1,
KCNK12,
SMOC2
|
| 18676988 |
A high-density association screen of 155 ion transport genes for involvement with common migraine. Hum Mol Genet Dale R Nyholt , K Steven LaForge , Mikko Kallela , Kirsi Alakurtti , Verneri Anttila , Markus Färkkilä , Eija Hämaläinen , Jaakko Kaprio , Mari A Kaunisto , Andrew C Heath , Grant W Montgomery , Hartmut Göbel , Unda Todt , Michel D Ferrari , Lenore J Launer , Rune R Frants , Gisela M Terwindt , Boukje de Vries , W M Monique Verschuren , Jan Brand , Tobias Freilinger , Volker Pfaffenrath , Andreas Straube , Dennis G Ballinger , Yiping Zhan , Mark J Daly , David R Cox , Martin Dichgans , Arn M J M van den Maagdenberg , Christian Kubisch , Nicholas G Martin , Maija Wessman , Leena Peltonen , Aarno Palotie |
2008-11-01 | - |
| 18209473 |
Cell. Physiol. Biochem. Franziska Theilig , Irena Goranova , Jochen R Hirsch , Martin Wieske , Semanur Unsal , Sebastian Bachmann , Rudiger W Veh , Christian Derst |
2008-01-01 | - |
| 17081983 |
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell Jesper V Olsen , Blagoy Blagoev , Florian Gnad , Boris Macek , Chanchal Kumar , Peter Mortensen , Matthias Mann |
2006-11-03 |
NR2E3,
ABI1,
TANK,
LINC00322,
CHAF1A,
TOM1,
DNAJB6,
SCAMP3,
HUWE1,
TSSC4,
COL4A3BP,
RAD50,
KIF20A,
PDIA6,
OPTN,
RBM12,
YAF2,
G3BP1,
ADGRG2,
CEBPZ,
PLXNC1,
TRIM28,
WASF2,
SORBS3,
RBM6,
RBM5,
CDK3,
TNK2,
MPHOSPH10,
MPHOSPH6,
TOPORS,
SRRM1,
STAM2,
ABCC4,
AKAP8,
STUB1,
UBE4B,
BET1,
SF3A1,
DNAJA2,
PAK4,
KATNB1,
ZNF267,
RTN3,
ADAR,
TRDN,
NPM3,
TUBB4B,
NDRG1,
BASP1,
YAP1,
CD2BP2,
PGRMC2,
SEC24B,
RBM14,
MCRS1,
CLGN,
LRRC41,
NCOA2,
SEMA4D,
SEMA4B,
MYBBP1A,
NOP56,
ANP32B,
RPP30,
ARFGEF2,
ARFGEF1,
CENPA,
DNPH1,
CENPC,
CDC42EP3,
PDLIM5,
TRIM3,
CENPE,
CENPF,
GAS2L1,
IGF2BP1,
KHDRBS3,
KHDRBS1,
CTCF,
CETN2,
USP39,
POLD3,
CFL1,
NUDC,
PTGES3,
CFL2,
STAG2,
RAI1,
KIF1C,
NUP50,
NES,
SRSF10,
WDR4,
SEPT9,
HSPH1,
UTP14A,
FAXDC2,
PPP1R13L
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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