| Type | Description |
|---|---|
| Definition | transmembrane serine protease 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:25:00 | COVID19 and SARSCoV2 host cell entry mediators: Expression profiling of TMRSS4 in health and disease. | 33649798 |
| 2021-02-13 13:22:00 | Role of miR-541-3p/TMPRSS4 in the metastasis and EMT of hepatocellular carcinoma. | 31858539 |
| 2020-10-31 13:12:00 | Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1. | 31659178 |
| 2020-05-23 10:57:00 | SARS-CoV-2 infects human mature enterocytes from the apical surface and triggers epithelial cell fusion. TMPRSS2 and TMPRSS4 serine proteases mediate this process by inducing cleavage of the S protein and enhancing membrane fusion. | 32404436 |
| 2020-05-16 10:57:00 | Down-regulation of TMPRSS4 increases triple negative breast cancer cell radiosensitivity and the use of TMPRSS4 inhibitor can be encouraged for improving radiotherapy effectiveness in triple negative breast cancer radioresistant patients. | 31870109 |
| Type | IDs |
|---|---|
| Synonymous | CAPH2, MT-SP2, TMPRSS3 |
| Gene |
UniProtKB-ID:
TMPS4_HUMAN,
B7Z900_HUMAN,
B7Z458_HUMAN,
B7Z8X1_HUMAN
UniprotKB:
Q9NRS4,
B7Z900,
B7Z458,
B7Z8X1
UniParc:
UPI00001FA467,
UPI0001AE6CC5,
UPI00019151BB,
UPI0001915495,
UPI0001914F8C,
UPI0001E8F3FE,
UPI0000E00039
EMBL:
AF179224,
EF445038,
AP000665,
AK172766,
BC004855,
BC011703,
AY358530,
AF216312,
AK304215,
AK304113,
AP002800,
AK296855,
AK303173
Ensembl:
ENSG00000137648
KO:
hsa:56649
|
| Nucleutide sequences |
EMBL-CDS:
BAH13911.1,
AAH11703.1,
AAF74526.1,
AAH04855.1,
AAQ88894.1,
AAF31436.1,
ACA06088.1,
BAD18749.1,
BAH14136.1,
BAH12444.1,
BAH14107.1
Gene_ORFName:
UNQ776/PRO1570
Ensembl_TRS:
ENST00000437212,
ENST00000522824,
ENST00000534111,
ENST00000618855,
ENST00000523251
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429209,
ENSP00000416037,
ENSP00000477949,
ENSP00000435184,
ENSP00000430547
RefSeq:
XP_011541206.1,
NP_001077416.2,
XP_005271671.1,
XP_011541203.1,
XP_005271670.1,
NP_001167023.2,
NP_063947.2,
NP_001277023.2,
XP_011541205.1,
XP_011541204.1,
XP_005271672.1,
NP_001277025.2,
NP_001167022.2
|
| Others |
UniRef100:
UniRef100_B7Z8X1,
UniRef100_B7Z900,
UniRef100_Q9NRS4,
UniRef100_B7Z458
UniRef90:
UniRef90_B7Z458,
UniRef90_Q9NRS4
UniRef50:
UniRef50_Q9NRS4,
UniRef50_A0A2K6FPG6
UniGene:
Hs.161985
CCDS:
CCDS31684.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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