| Type | Description |
|---|---|
| Definition | BRCA2 and CDKN1A interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:28:00 | BCCIPbeta facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma. | 32736693 |
| 2021-01-16 16:00:00 | BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis. | 33245766 |
| 2019-06-15 10:36:00 | BCCIP stabilized YY1 protein in colorectal cancer cells.Transcriptional regulation of BCCIP was associated with its ability to stabilize YY1.BCCIP promoter region contains YY1 binding site (CCGCCATC).BCCIP binds to and activates its promoter in a YY1-dependent fashion. | 29932276 |
| 2018-06-09 10:05:00 | We analyzed the BCCIP protein level in 470 cases of human breast cancer to determine the associations between BCCIP and 53BP1, p53, and subtypes of breast cancer. We further constructed a unique BCCIP knockdown mouse model to determine whether a partial BCCIP deficiency leads to spontaneous breast cancer formation | 29047390 |
| 2018-04-07 10:26:00 | BCCIPbeta, as a S7 modulator, contributes to the regulation of ribosomal and extraribosomal functions of S7 and has implications in cell growth and tumor development. | 28510697 |
| Type | IDs |
|---|---|
| Synonymous | TOK-1, TOK1 |
| Gene |
UniProtKB-ID:
BCCIP_HUMAN
UniprotKB:
Q9P287
UniParc:
UPI000006FB06,
UPI0000073C44,
UPI0000DE1F7F,
UPI0000073C58
EMBL:
AY064248,
AK055691,
AY064247,
AB040451,
AL360176,
BC009771,
AB040450,
AL834458,
AY064249
Ensembl:
ENSG00000107949
KO:
hsa:56647
|
| Nucleutide sequences |
EMBL-CDS:
AAL55438.1,
CAD39118.1,
AAH09771.1,
BAA92928.1,
AAL55436.1,
BAA92927.1,
AAL55439.1,
AAL55440.1,
BAG51557.1
Ensembl_TRS:
ENST00000368759,
ENST00000278100,
ENST00000299130
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000299130,
ENSP00000278100,
ENSP00000357748
RefSeq:
NP_057651.1,
NP_510868.1,
NP_510869.1
|
| Others |
UniRef100:
UniRef100_Q9P287
UniRef90:
UniRef90_Q9P287
UniRef50:
UniRef50_Q9P287
UniGene:
Hs.370292,
Hs.715543
CCDS:
CCDS7651.1,
CCDS7649.1,
CCDS7650.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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