| Type | Description |
|---|---|
| Definition | ankyrin repeat domain 2 (stretch responsive muscle) |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 11:22:00 | We describe a novel mechanism of signal transduction enriched in medium spiny neurons of striatum that likely mediates effects of the neurotransmitter dopamine acting on these cells. We find that the protein which is highly expressed in striatal medium spiny neurons, acts as a selective inhibitor of certain forms of the serine/threonine protein phosphatase, PP2A, when phosphorylated by the kinase, MAST3. | 28167675 |
| 2015-01-10 14:17:00 | Ankrd2, and are not essential for normal cardiac development and function at basal conditions and in response to mechanical pressure overload. | 24736439 |
| 2014-09-06 11:02:00 | Ankrd2 as a potent repressor of inflammatory responses through direct interaction with the NF-kappaB repressor subunit p50. | 24434510 |
| 2013-11-16 11:20:00 | a novel pathway in which SREBP-1/ANKRD2/ID3 activation inhibits myoblast differentiation, and we propose that this pathway acts as a critical determinant of the skeletal muscle developmental program. | 23824195 |
| 2010-01-21 00:00:00 | The Ankrd2 accumulated in the nuclei of myofibers located adjacent to severely damaged myofibers after muscle injury. Ankrd2 may translocate from the I-band to the nucleus in response to muscle damage and in the regulation of gene expression. | 17926058 |
| Type | IDs |
|---|---|
| Synonymous | Arpp |
| Gene |
UniProtKB-ID:
ANKR2_MOUSE
UniprotKB:
Q9WV06
UniParc:
UPI0000022558
EMBL:
AB076257,
AJ245514,
AK132585,
AJ011118,
AJ249346,
BC138760,
AC133503,
AB076256,
BC138761,
CH466534
Ensembl:
ENSMUSG00000025172
KO:
mmu:56642
|
| Nucleutide sequences |
EMBL-CDS:
BAB88558.1,
BAB88557.1,
AAI38761.1,
EDL41876.1,
CAB99431.1,
BAE21246.1,
AAI38762.1,
CAB99432.1,
CAB46646.1
Ensembl_TRS:
ENSMUST00000026172
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026172
RefSeq:
XP_017173753.1,
XP_006527297.1,
NP_064417.2
|
| Others |
UniRef100:
UniRef100_Q9WV06
UniRef90:
UniRef90_Q9WV06
UniRef50:
UniRef50_Q9WV06
UniGene:
Mm.143737
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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