| Type | Description |
|---|---|
| Definition | inositol polyphosphate-5-phosphatase E |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 11:30:00 | Formation of primary cilia is downregulated in TULP3-knockout (KO) RPE1 cells. ARL13B and INPP5E fail to localize to primary cilia in TULP3-KO cells. | 30583862 |
| 2018-08-25 12:09:00 | miR598 contributed to cell proliferation and cell cycle progression in colorectal carcinoma by targeting INPP5E. | 29257251 |
| 2018-03-03 11:48:00 | INPP5E associates with the N-terminus of RPGR and trafficking of INPP5E to cilia is dependent upon the ciliary localization of RPGR. | 28172980 |
| 2017-09-30 11:15:00 | we identify Inpp5e as an essential inhibitor of the PI3K/Akt/mTORC1 signaling axis in renal epithelial cells, and demonstrate a critical role for Inpp5e-dependent mTORC1 regulation in Polycystic kidney disease (PKD) suppression | 27056978 |
| 2017-08-05 10:29:00 | ARL13B regulates IFT-A-mediated retrograde protein trafficking within cilia through its interaction with INPP5E. | 27927754 |
| Type | IDs |
|---|---|
| Synonymous | CORS1, CPD4, JBTS1, MORMS, PPI5PIV, pharbin |
| Gene |
UniProtKB-ID:
INP5E_HUMAN
UniprotKB:
Q9NRR6
UniParc:
UPI000181EEEB,
UPI000014053C
EMBL:
AF187891,
CH471090,
AL592301,
BC028032,
U45974
Ensembl:
ENSG00000148384
KO:
hsa:56623
|
| Nucleutide sequences |
EMBL-CDS:
AAH28032.1,
EAW88234.1,
AAB03215.1,
AAF81404.1
Ensembl_TRS:
ENST00000371712
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360777
RefSeq:
NP_001305431.1,
NP_063945.2,
XP_016870415.1
|
| Others |
UniRef100:
UniRef100_Q9NRR6
UniRef90:
UniRef90_Q9NRR6
UniRef50:
UniRef50_Q9NRR6
UniGene:
Hs.120998
CCDS:
CCDS7000.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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