| Type | Description |
|---|---|
| Definition | pleckstrin and Sec7 domain containing |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:14:00 | The C-terminal domain of EFA6A interacts directly with F-actin and assembles F-actin bundles. | 31844082 |
| 2019-08-10 12:27:00 | EFA6A recruits alpha-actinin 1 (ACTN1) through direct binding. | 29246944 |
| 2016-09-24 12:13:00 | Arf GTPases are likely to be locally activated by EFA6 and in turn targeted to the Flemming body to complete cytokinesis. | 26330566 |
| 2015-08-15 10:30:00 | PSD expression might be a useful biomarker for epigenetic-based gastric cancer early diagnosis and may lead to the identification of new targets for pharmacological intervention. | 25355626 |
| 2014-11-29 10:08:00 | EFA6 is regulated by a negative feedback loop, which is mediated by an allosteric interaction of Arf6-GTP with a domain of EFA6 and monitors the activation of Arf1 and Arf6 differentially | 25114232 |
| Type | IDs |
|---|---|
| Synonymous | EFA6, EFA6A, PSD1, TYL |
| Gene |
UniProtKB-ID:
PSD1_HUMAN,
Q86YI3_HUMAN
UniprotKB:
A5PKW4,
Q86YI3
UniParc:
UPI000007082E,
UPI000056D450,
UPI0000404928
EMBL:
AL121928,
AB095931,
BC039259,
X99688,
BC142689,
BC142643,
CH471066
Ensembl:
ENSG00000059915
KO:
hsa:5662
|
| Nucleutide sequences |
EMBL-CDS:
CAA68002.1,
BAC23107.1,
AAI42644.1,
EAW49693.1,
EAW49694.1,
AAI42690.1,
AAH39259.2
Ensembl_TRS:
ENST00000611678,
ENST00000406432,
ENST00000020673
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000481250,
ENSP00000020673,
ENSP00000384830
RefSeq:
XP_016871923.1,
NP_002770.3,
XP_011538270.1,
XP_016871922.1,
NP_001257894.1,
XP_011538271.1,
NP_001257895.1
|
| Others |
UniRef100:
UniRef100_Q86YI3,
UniRef100_A5PKW4
UniRef90:
UniRef90_A5PKW4,
UniRef90_Q86YI3
UniRef50:
UniRef50_Q86YI3,
UniRef50_A5PKW4
UniGene:
Hs.154658,
Hs.743732
CCDS:
CCDS73187.1,
CCDS31272.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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