| Type | Description |
|---|---|
| Definition | diablo IAP-binding mitochondrial protein |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma. | 32054850 |
| 2021-02-27 13:47:00 | Future Therapeutic Directions for Smac-Mimetics. | 32053868 |
| 2020-10-03 12:52:00 | Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein. | 31744505 |
| 2020-06-27 12:15:00 | Smac plays an important role in the development of Primary Sjogren's syndrome (pSS). | 31274785 |
| 2020-04-04 10:34:00 | NF-kappaB activation by Smac mimetic contributes to Smac mimetic-mediated protection against TM-induced apoptosis. | 30680482 |
| Type | IDs |
|---|---|
| Synonymous | DFNA64, SMAC |
| Gene |
UniProtKB-ID:
DBLOH_HUMAN,
A0A0S2Z5U7_HUMAN,
A0A024RBT2_HUMAN,
K7X1S0_HUMAN,
A0A0S2Z5P6_HUMAN,
Q502X2_HUMAN
UniprotKB:
Q9NR28,
A0A0S2Z5U7,
A0A024RBT2,
K7X1S0,
A0A0S2Z5P6,
Q502X2
UniParc:
UPI00001FB8A1,
UPI000013FD9C,
UPI000002B3D4,
UPI0000000CBE,
UPI00029B98F3
EMBL:
AK001399,
AF262240,
AC048338,
AF298770,
AK315629,
AK057778,
KU178726,
BC095468,
CH471054,
BC004417,
BC011909,
JX679472,
KU178725,
AK024768,
AY313210
Ensembl:
ENSG00000184047
KO:
hsa:56616
|
| Nucleutide sequences |
EMBL-CDS:
AAH04417.1,
AAF87716.1,
BAB71568.1,
BAG37997.1,
AAQ86939.1,
BAB14994.1,
AAG22077.1,
AAH11909.1,
ALQ34183.1,
EAW98314.1,
EAW98313.1,
EAW98316.1,
AFX61342.1,
ALQ34184.1,
EAW98315.1,
BAG50903.1,
AAH95468.1
Gene_ORFName:
hCG_1782202,
hCG_1782202
Ensembl_TRS:
ENST00000650715,
ENST00000353548,
ENST00000464942,
ENST00000443649
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320343,
ENSP00000499058,
ENSP00000442360,
ENSP00000398495
RefSeq:
NP_063940.1,
NP_001265231.1,
NP_001265233.1,
NP_001265271.1,
NP_620308.1,
NP_001265232.1,
NP_001358262.1
|
| Others |
UniRef100:
UniRef100_Q9NR28-3,
UniRef100_Q502X2,
UniRef100_K7X1S0,
UniRef100_Q9NR28
UniRef90:
UniRef90_Q9NR28,
UniRef90_K7X1S0,
UniRef90_Q9NR28-3,
UniRef90_Q502X2
UniRef50:
UniRef50_Q9NR28,
UniRef50_K7X1S0,
UniRef50_Q9NR28-3,
UniRef50_A0A226NA45
UniGene:
Hs.169611
CCDS:
CCDS9229.1,
CCDS9228.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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