| Type | Description |
|---|---|
| Definition | nuclear receptor subfamily 1, group I, member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:21:00 | The Pxr variants differed in both their ability to bind these structurally different ligands and to regulate reporter gene expression in vitro. We infer that the observed sequence variations in zebrafish Pxrs likely affect the response to putative Pxr agonists in vivo and potentially cause strain-specific biotransformation of xenobiotics in zebrafish. | 30371853 |
| 2015-10-03 11:37:00 | Selected zebrafish CYP1, CYP2 and CYP3 genes appear to be under the regulation of both pregnane X receptor and aryl hydrocarbon receptor 2. | 25424564 |
| 2014-03-22 11:07:00 | CYP3A65 and PXR may be involved in the metabolization and detoxification of microcystins in zebrafish, which may be regulated by dre-miR-27b. | 23851223 |
| 2010-01-21 00:00:00 | similar pattern of mRNA expression of PXR, cytochrome P4503A and multiple drug resistance 1 genes found in fish treated with different PXR inducers suggests that the intrinsic association between these three genes is conserved in zebrafish | 15914091 |
| Type | IDs |
|---|---|
| Synonymous | PXR |
| Gene |
UniProtKB-ID:
A5WYG8_DANRE,
B0V1H8_DANRE
UniprotKB:
A5WYG8,
B0V1H8
UniParc:
UPI00015386B0,
UPI00015D475F
EMBL:
CR848676,
DQ069792
Ensembl:
ENSDARG00000029766
KO:
dre:565875
|
| Nucleutide sequences |
EMBL-CDS:
AAY89057.1
Ensembl_TRS:
ENSDART00000125174,
ENSDART00000061525
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000061524,
ENSDARP00000106185
RefSeq:
XP_005167477.1,
XP_021334399.1,
NP_001092087.2
|
| Others |
UniRef100:
UniRef100_B0V1H8,
UniRef100_A5WYG8
UniRef90:
UniRef90_B0V1H8
UniRef50:
UniRef50_B0V1H8
UniGene:
Dr.27060
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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