| Type | Description |
|---|---|
| Definition | kallikrein related peptidase 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:33:00 | Kallikrein-related peptidase (KLK10) cessation blunts colorectal cancer cell growth and glucose metabolism by regulating the PI3K/Akt/mTOR pathway. | 32386481 |
| 2020-05-23 12:32:00 | The data suggest that via inhibition of BCL-2 expression, overexpressed NES1 might enhance the effect of radiation therapy of (131)I uptake in hNIS overexpressed PC3 cells. | 31119602 |
| 2019-05-18 11:24:00 | findings show that KLK10 promotes trastuzumab resistance, at least in part, through the PI3K/AKT signaling pathway, suggesting that KLK10 is a potentially target to overcome trastuzumab resistance, and the combination might overcome trastuzumab resistance in KLK10-overexpressed gastric cancer patients. | 29231994 |
| 2018-12-22 11:08:00 | MiR-199b-5p promotes cell proliferation, migration and suppresses apoptosis in cervical cancer cells. KLK10 is a direct target of miR-199b-5p. MiR-199b-5p expression is increased and positively correlated with KI-67 in human cervical cancer tissues and cell lines. | 29807015 |
| 2018-10-13 12:03:00 | blockade of KLK10 attenuates epithelial-mesenchymal transition and activation of FAK-SRC-ERK signaling, which explains the mechanism of KLK10 in promoting metastasis. | 29621546 |
| Type | IDs |
|---|---|
| Synonymous | NES1, PRSSL1 |
| Gene |
UniProtKB-ID:
KLK10_HUMAN
UniprotKB:
O43240
UniParc:
UPI000013CCB0
EMBL:
AF024605,
BC002710,
AF243527,
AY561635,
AF055481,
AC011473
Ensembl:
ENSG00000129451
KO:
hsa:5655
|
| Nucleutide sequences |
EMBL-CDS:
AAS66976.1,
AAB81602.1,
AAH02710.1,
AAC14266.1,
AAG33363.1,
AAG23256.1
Ensembl_TRS:
ENST00000309958,
ENST00000358789,
ENST00000391805
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000351640,
ENSP00000375681,
ENSP00000311746
RefSeq:
XP_005259118.1,
NP_001070968.1,
NP_665895.1,
NP_002767.2,
XP_005259119.1,
XP_016882482.1,
XP_006723352.1,
XP_006723350.1
|
| Others |
UniRef100:
UniRef100_O43240
UniRef90:
UniRef90_O43240
UniRef50:
UniRef50_O43240
UniGene:
Hs.275464
CCDS:
CCDS12817.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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