| Type | Description |
|---|---|
| Definition | intestinal cell kinase |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 11:59:00 | Loss of ICK function markedly reduced mineralization in the spinal column, ribs, and long bones | 29098359 |
| 2018-11-10 10:49:00 | These results suggest that Ick is expressed in proliferating regions in the adult mouse brain, testis, and intestine. | 29635032 |
| 2017-09-23 10:50:00 | Data indicate an essential role for intestinal cell kinase (ICK) in lung development and advances the mechanistic understanding of endocrine-cerebro-osteodysplasia (ECO) syndrome. | 28380258 |
| 2017-08-19 11:36:00 | The results of this study found that loss of Ick leads to abnormal localization of the IFT component in kinocilia, PCP defects in HCs, and hearing dysfunction. | 28115485 |
| 2015-12-05 10:59:00 | findings suggest that increased ICK expression/activity in response to protein deprivation likely provides a novel protective mechanism to limit apoptosis and support compensatory mucosal growth under nutritional stress. | 25184386 |
| Type | IDs |
|---|---|
| Synonymous | 2210420N10Rik, AI848300, Mrk |
| Gene |
UniProtKB-ID:
CILK1_MOUSE,
Q69ZV0_MOUSE
UniprotKB:
Q9JKV2,
Q69ZV0
UniParc:
UPI00003FEF82,
UPI00000E7D68
EMBL:
AF225918,
AK173068,
BC028863
Ensembl:
ENSMUSG00000009828
KO:
mmu:56542
|
| Nucleutide sequences |
EMBL-CDS:
AAH28863.1,
AAF37277.1,
BAD32346.1
Ensembl_TRS:
ENSMUST00000118869,
ENSMUST00000044551
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048234,
ENSMUSP00000112961
RefSeq:
XP_030100326.1,
XP_030100325.1,
NP_064371.2,
NP_001157252.1,
XP_006511367.1
|
| Others |
UniRef100:
UniRef100_Q9JKV2
UniRef90:
UniRef90_Q9JKV2
UniRef50:
UniRef50_Q9JKV2
UniGene:
Mm.288719
CCDS:
CCDS40697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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