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5652 PRSS8

5652

PRSS8

serine protease 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine protease 8

研究结论

Date Results Publications
2021-03-13 13:21:00 Insights into the regulation of the matriptase-prostasin proteolytic system. 33094801
2019-05-11 13:07:00 Compared with normal mucosa, PRSS8 mRNA levels were significantly reduced in colorectal adenocarcinomas. It was reduced in poorly differentiated cancers and in lymph node metastatic cancers in a progressive colorectal cancer tissue microarray. 30115975
2018-04-14 10:48:00 limited role for HAI-2 in the inhibition of matriptase and prostasin is the result of its primarily intracellular localization in basal and spinous layer keratinocytes, which probably prevents the Kunitz inhibitor from interacting with active prostasin or matriptase 29438412
2018-03-31 11:39:00 PRSS8 was downregulated in glioma tissues.PRSS8 role in the glioma cell proliferation, migration, and invasion. 27983922
2018-01-06 10:52:00 PRSS8 acts as a tumor suppressor in colorectal cancer 27050145

名称对应

Type IDs
Synonymous CAP1, PROSTASIN
Gene
UniProtKB-ID: PRSS8_HUMAN
UniprotKB: Q16651
UniParc: UPI0000046DCB, UPI00017A8119
EMBL: AK301619, BC001462, AC009088, L41351, U33446
Ensembl: ENSG00000052344
KO: hsa:5652
Nucleutide sequences
EMBL-CDS: AAH01462.1, AAC41759.1, BAG63104.1, AAB19071.1
Ensembl_TRS: ENST00000568261, ENST00000317508
Protein sequencees
Ensembl_PRO: ENSP00000457750, ENSP00000319730
RefSeq: NP_002764.1
Others
UniRef100: UniRef100_Q16651
UniRef90: UniRef90_Q16651
UniRef50: UniRef50_Q16651
UniGene: Hs.75799
CCDS: CCDS45469.1

全选

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研究热度

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