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5651 TMPRSS15

5651

TMPRSS15

transmembrane serine protease 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition transmembrane serine protease 15

研究结论

Date Results Publications
2019-04-13 11:42:00 Enterokinases was able to enhance the proliferation of H1N1 virus in 293T human kidney cells, but the proliferation was reduced by knocking down the endogenous enterokinase in A549 cells. 29629340
2013-11-16 12:00:00 The Y174R variant showed improved specificities for substrates containing the sequences DDDDK (kcat/KM = 6.83 x 106 M-1 sec-1) and DDDDR (kcat/KM = 1.89 x 107 M-1 sec-1) relative to all other enteropeptidase variants reported to date. 23436726
2013-05-25 10:32:00 Enteropeptidase is a gene associated with a starvation human phenotype and a novel target for obesity treatment 23185382
2012-12-08 11:04:00 Human enteropeptidase shows 10x faster kinetics compared to other animal sources but low solubility under low salt conditions. A supercharged variant of enteropeptidase light chain with increased solubility was used for crystallization. 22488687
2012-08-18 10:43:00 Characterization of the different catalytic activity of human and bovine enteropeptidase light chains toward hydrolysis of peptides and proteins lacking tetraaspartate sequence. 22571433

名称对应

Type IDs
Synonymous ENTK, PRSS7
Gene
UniProtKB-ID: ENTK_HUMAN
UniprotKB: P98073
UniParc: UPI000013DDBE
EMBL: Y19140, Y19124, Y19139, Y19126, Y19141, Y19135, AL163217, Y19127, Y19130, U09860, Y19143, Y19128, Y19133, Y19129, BC111749, Y19142, Y19132, Y19138, Y19136, Y19131, Y19134, Y19125, AL163218, Y19137
Ensembl: ENSG00000154646
KO: hsa:5651
Nucleutide sequences
EMBL-CDS: CAB65555.1, CAB90389.1, CAB90392.1, AAI11750.1, AAC50138.1
Ensembl_TRS: ENST00000284885
Protein sequencees
Ensembl_PRO: ENSP00000284885
RefSeq: NP_002763.3, XP_011527960.1, XP_011527959.1, XP_011527957.1, XP_011527956.1, XP_011527961.1, XP_011527958.1
Others
UniRef100: UniRef100_P98073
UniRef90: UniRef90_P98073
UniRef50: UniRef50_P98073
UniGene: Hs.149473
CCDS: CCDS13571.1

全选

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