| Type | Description |
|---|---|
| Definition | RuvB-like protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:25:00 | Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression. | 31721195 |
| 2021-01-09 13:34:00 | Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy. | 33293536 |
| 2019-03-30 11:50:00 | inducible deletion of Ruvbl1 in cells carrying motile cilia results in hydrocephalus, suggesting functional relevance in both primary and motile cilia. Cilia of Ruvbl1-negative cells lack crucial proteins, consistent with the concept of Ruvbl1-dependent cytoplasmic pre-assembly of ciliary protein complexes. | 29959317 |
| 2018-01-06 10:49:00 | In mouse testis, Pontin is essential for the stabilization of axonemal dynein intermediate chain 1 (DNAI1) and DNAI2, the first appreciated step in axonemal dynein arm assembly. | 29113992 |
| 2016-07-02 10:03:00 | accumulating E2f1 progressively recruits a Pontin/Reptin complex to open the chromatin conformation at E2f target genes and amplifies the E2f transcriptional response. | 26639898 |
| Type | IDs |
|---|---|
| Synonymous | 2510009G06Rik, Pontin52, Tip49a |
| Gene |
UniProtKB-ID:
RUVB1_MOUSE,
Q3U1C2_MOUSE
UniprotKB:
P60122,
Q3U1C2
UniParc:
UPI0000029B3E
EMBL:
AK156078,
BC004718,
AK132783,
AF100694
Ensembl:
ENSMUSG00000030079
KO:
mmu:56505
|
| Nucleutide sequences |
EMBL-CDS:
AAH04718.1,
AAD02877.1,
BAE21358.1,
BAE33576.1
Ensembl_TRS:
ENSMUST00000032165
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032165
RefSeq:
NP_062659.1
|
| Others |
UniRef100:
UniRef100_P60122
UniRef90:
UniRef90_P60122
UniRef50:
UniRef50_P60122
UniGene:
Mm.42195
CCDS:
CCDS20336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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