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5650 KLK7

5650

KLK7

kallikrein related peptidase 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition kallikrein related peptidase 7

研究结论

Date Results Publications
2021-02-06 13:49:00 Extracellular acidityinduced expression of Kallikreinrelated peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells. 32323843
2021-01-09 13:26:00 Kallikrein 7 Promotes Atopic Dermatitis-Associated Itch Independently of Skin Inflammation. 31883963
2020-01-18 11:31:00 Biochemical validation supports a role for KLK7 in directly activating pro-MMP10, hydrolysis of IGFBP6 and cleavage of thrombospondin 1 with generation of a potentially bioactive N-terminal fragment. 30705123
2019-10-05 12:44:00 KLK7 accelerated the deterioration of PTC in vitro experiments which could be reversed by sh-lnc RNA NEAT1 and miR-129-5p mimics. In vivo experiments, silence of lncRNA NEAT1 restrain tumor growth in weight and volume. 29319165
2019-05-25 10:04:00 Structures of BbKI complexed with the catalytic domain of human plasma kallikrein were modeled, as well as those with KLK4 and KLK7, and the structures were analyzed in order to identify the interactions that are responsible for inhibitory potency. 30644845

名称对应

Type IDs
Synonymous PRSS6, SCCE, hK7
Gene
UniProtKB-ID: KLK7_HUMAN, B4DHX9_HUMAN, A0A024R4H6_HUMAN
UniprotKB: P49862, B4DHX9, A0A024R4H6
UniParc: UPI00017A7124, UPI000007360E, UPI0000001BC4
EMBL: L33404, AF411214, AF332583, AF243527, AY601109, AK289660, AF166330, AF411215, AK295313, BC032005, LT631555, CH471135
Ensembl: ENSG00000169035
KO: hsa:5650
Nucleutide sequences
EMBL-CDS: AAN03663.1, AAK69624.1, AAD49718.1, AAN03662.1, AAU04540.1, EAW71959.1, AAH32005.1, BAF82349.1, AAG33360.1, AAC37551.1, BAG58291.1, EAW71960.1, EAW71961.1, SFW93202.1
Gene_ORFName: hCG_22936
Ensembl_TRS: ENST00000595820, ENST00000391807, ENST00000597707
Protein sequencees
Ensembl_PRO: ENSP00000470538, ENSP00000375683, ENSP00000469950
RefSeq: NP_005037.1, NP_644806.1, NP_001230055.1, NP_001193982.1
Others
UniRef100: UniRef100_A0A2J8Q6J5, UniRef100_P49862
UniRef90: UniRef90_P49862, UniRef90_A0A2J8Q6J5
UniRef50: UniRef50_P49862, UniRef50_H9H5Q0
UniGene: Hs.151254
CCDS: CCDS12812.1, CCDS59414.1

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