| Type | Description |
|---|---|
| Definition | claudin 18 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:13:00 | Results found that Cldn18 deficiency induced the development of gastric tumors under chronic active gastritis in the absence of H pylori infection. Age-dependent changes in several signaling networks involving inflammation-, stemness-, and Wnt-related pathways, may accelerate this gastric tumorigenesis in a multi-faceted manner. | 30910700 |
| 2019-11-30 10:21:00 | expression associated with peripheral lung epithelial cell maturation and plays a key role in the corticosteroid-induced expression of surfactant proteins | 29082763 |
| 2019-07-20 12:59:00 | claudin family member highly expressed in lung alveolar epithelium, leads to lung enlargement, parenchymal expansion, increased abundance and proliferation of known distal lung progenitors, the alveolar epithelial type II (AT2) cells, activation of Yes-associated protein (YAP), increased organ size, and tumorigenesis in mice | 29400695 |
| 2019-07-20 11:50:00 | Lack of CAIX results in persistent acid backflux via claudin-18 downregulation, causing loss of parietal cells, hypergastrinaemia and foveolar hyperplasia. | 28748627 |
| 2017-07-22 11:12:00 | The presented data substantiate the hypothesis that claudin-18 is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18. These data also suggest that the loss of claudin-18 is associated with increased sensitization to aeroantigens and airway responsiveness | 27215490 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CLD18_MOUSE,
Q8BZS5_MOUSE
UniprotKB:
P56857,
Q8BZS5
UniParc:
UPI000002A6AB,
UPI0000023ABE,
UPI000002A6AD,
UPI00000EA3B8,
UPI000002A6AC
EMBL:
AF349453,
AF349450,
AF349451,
AF221068,
AK033657
Ensembl:
ENSMUSG00000032473
KO:
mmu:56492
|
| Nucleutide sequences |
EMBL-CDS:
AAL15638.1,
AAL15635.1,
AAF26447.1,
AAL15636.1,
BAC28412.1
Ensembl_TRS:
ENSMUST00000112882,
ENSMUST00000035048,
ENSMUST00000131922,
ENSMUST00000136429
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108503,
ENSMUSP00000117382,
ENSMUSP00000035048,
ENSMUSP00000115782
RefSeq:
NP_001181852.1,
NP_001181850.1,
NP_001181851.1,
NP_062789.1
|
| Others |
UniRef100:
UniRef100_Q8BZS5,
UniRef100_P56857
UniRef90:
UniRef90_P56857
UniRef50:
UniRef50_P56857
UniGene:
Mm.386784
CCDS:
CCDS23437.1,
CCDS57692.1,
CCDS57693.1,
CCDS57694.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员