| Type | Description |
|---|---|
| Definition | vesicle-associated membrane protein, associated protein B and C |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy. | 32525583 |
| 2020-12-05 12:59:00 | Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation. | 32376919 |
| 2019-10-19 11:16:00 | There was colocalization of Kv2.1 and Kv2.2 with endogenous VAPB at ER-PM junctions in mouse brain neurons. Expression of Kv2.1 recruits VAPB to ER-PM junctions.The domains of VAPs and Kv2.1 necessary and sufficient for their association at ER-PM junctions were identified. | 30012696 |
| 2019-06-01 11:49:00 | Peroxisomal (PO) long range movements were largely diminished in response to human ACBD5 overexpression in primary mouse hippocampal neurons. PO localization significantly changed in ACBD5-transfected neurons, PO numbers in neurites increased, while PO density in the soma was decreased. Alterations in PO motility and distribution in the hippocampal neurons were independent of the interaction between ACBD5 and mouse Vapb. | 30589881 |
| 2019-03-02 10:11:00 | ignificant alterations of the vesicle-associated membrane protein-associated protein B (VAPB) and its downstream pathways such as mitochondrial calcium uptake and autophagy were detected in dominant GARS mutations. The role of VAPB has been supported by similar results in the GarsC210R mice. Our data suggest that altered mitochondria-associated endoplasmic reticulum (ER) membranes (MAM) may be important disease mechanisms | 29648643 |
| Type | IDs |
|---|---|
| Synonymous | AI225786, AI840687, AI848259, D2Abb2e, R75548, VAP33b, Vamp33b |
| Gene |
UniProtKB-ID:
Q8BH80_MOUSE
UniprotKB:
Q8BH80
UniParc:
UPI00000EB960
EMBL:
BC057123,
AL844849,
AK050632,
AL845503,
BC048231,
AK081908
Ensembl:
ENSMUSG00000054455
KO:
mmu:56491
|
| Nucleutide sequences |
EMBL-CDS:
BAC38368.1,
BAC34353.1,
AAH57123.1,
AAH48231.1
Ensembl_TRS:
ENSMUST00000067530
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064699
RefSeq:
NP_062780.2
|
| Others |
UniRef100:
UniRef100_Q8BH80
UniRef90:
UniRef90_Q9QY76
UniRef50:
UniRef50_Q9QY76
UniGene:
Mm.260456
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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