| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily Q member 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Remodeling of Kv7.1 and Kv7.5 Expression in Vascular Tumors. | 32825637 |
| 2020-04-25 10:13:00 | Distinct functional domains were identified that confer differential sensitivities of Kv7.5 and Kv7.4 to stimulatory and inhibitory signaling. | 31871302 |
| 2018-12-22 11:35:00 | Phylogenetic analysis, electrostatic potential mapping, in silico docking, electrophysiology, and radioligand binding assays reveal that the anticonvulsant binding pocket evolved to accommodate endogenous neurotransmitters including gamma-aminobutyric acid, which directly activates KCNQ5 and KCNQ3 via W265. | 29748663 |
| 2018-11-10 10:49:00 | Phosphorylation of S53 on the amino terminus of Kv7.5 is essential for protein kinase A-dependent enhancement of channel activity in response to beta adrenergic receptor activation in vascular and airway smooth muscle cells. | 30061510 |
| 2018-09-22 11:02:00 | identified P2RX2, KCNQ5, ERBB3 and SOCS3 to be associated with the progression of age-related hearing impairment | 29325454 |
| Type | IDs |
|---|---|
| Synonymous | Kv7.5, MRD46 |
| Gene |
UniProtKB-ID:
KCNQ5_HUMAN
UniprotKB:
Q9NR82
UniParc:
UPI0000EADF38,
UPI0001A47187,
UPI0000167EE4,
UPI000004365E,
UPI000155D644,
UPI000018CEC6,
UPI0000457466
EMBL:
AL365232,
AJ272510,
AJ272512,
AF249278,
BC050689,
AJ272508,
AJ272511,
AJ272513,
AJ272517,
AL513522,
AL671823,
AJ272516,
AJ272514,
AJ272507,
AF202977,
AJ272519,
AJ272518,
AL360232,
AL445569,
AL360236,
AJ272506,
BC117359,
AF263835,
AL049845,
AJ272509,
BC143554,
AK299550,
AJ272515,
FO393414
Ensembl:
ENSG00000185760
KO:
hsa:56479
|
| Nucleutide sequences |
EMBL-CDS:
AAF69797.1,
BAG61495.1,
CAC88112.1,
AAH50689.1,
AAF73446.1,
AAI17360.1,
AAI43555.1,
AAF91335.1
Ensembl_TRS:
ENST00000370398,
ENST00000342056,
ENST00000629977,
ENST00000370392,
ENST00000628967
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485743,
ENSP00000359425,
ENSP00000345055,
ENSP00000359419,
ENSP00000486187
RefSeq:
XP_024302260.1,
NP_001153606.1,
NP_001153602.1,
NP_062816.2,
XP_024302261.1,
NP_001153605.1,
XP_016866547.1,
NP_001153604.1
|
| Others |
UniRef100:
UniRef100_Q9NR82
UniRef90:
UniRef90_Q9NR82
UniRef50:
UniRef50_Q9NR82
UniGene:
Hs.445324
CCDS:
CCDS55035.1,
CCDS4976.1,
CCDS55034.1,
CCDS55037.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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