| Type | Description |
|---|---|
| Definition | CTP synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:49:00 | Cryo-EM structures reveal that CTPS2 filaments dynamically switch between active and inactive forms in response to changes in substrate and product levels. | 31873303 |
| 2011-09-24 11:51:00 | CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin. | 21252287 |
| 2011-07-09 10:05:00 | Low CTPS2 expression may be a rationally-based determinant of 5FU resistance. | 21378502 |
| 2010-11-27 10:09:00 | analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation | 20739275 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PYRG2_HUMAN,
A0A024RC00_HUMAN
UniprotKB:
Q9NRF8,
A0A024RC00
UniParc:
UPI0000073CBD
EMBL:
AF226667,
AK125348,
AC073909,
AL445467,
AK024070,
CH471074,
AK125332,
BC034986,
AK023549,
BC006256
Ensembl:
ENSG00000047230
KO:
hsa:56474
|
| Nucleutide sequences |
EMBL-CDS:
BAG54184.1,
EAW98912.1,
AAF91241.1,
BAG54188.1,
AAH06256.2,
BAB14607.1,
AAH34986.1,
BAB14814.1,
EAW98914.1,
EAW98915.1
Gene_ORFName:
hCG_1640699
Ensembl_TRS:
ENST00000380241,
ENST00000359276,
ENST00000443824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000401264,
ENSP00000352222,
ENSP00000369590
RefSeq:
XP_006724566.1,
NP_001137474.1,
XP_011543847.1,
NP_062831.3,
NP_787055.1,
XP_024308176.1,
XP_005274619.1,
XP_024308177.1
|
| Others |
UniRef100:
UniRef100_Q9NRF8
UniRef90:
UniRef90_Q9NRF8
UniRef50:
UniRef50_P17812
UniGene:
Hs.227049
CCDS:
CCDS14175.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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