| Type | Description |
|---|---|
| Definition | protein inhibitor of activated STAT 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:12:00 | The present study raises the possibility of different levels of PIAS1 between individuals in response to chronic social defeat stress and that such differences may contribute to the susceptibility to stress. | 30351951 |
| 2019-06-01 10:16:00 | These findings demonstrate the crucial role of PIAS1-mediated PPARgamma SUMOylation in protecting against myocardial ischemia-reperfusion injury. | 30419807 |
| 2017-09-23 10:11:00 | these results indicate that PIAS1 is a positive regulator of MYC. | 27239040 |
| 2017-08-26 12:56:00 | PIAS1 overexpression exacerbated mutant Huntingtin-associated phenotypes and aberrant protein accumulation | 27146268 |
| 2017-06-24 10:40:00 | Pias1 expression in primary myoblasts enhances the induction of cardiac muscle genes MyoD, Myogenin and Myomaker. Endothelial cell specific inactivation of Pias1 in vivo impairs yolk sac erythrogenesis, angiogenesis and recapitulates loss of myocardium muscle mass. Pias1 is an essential gene for YS erythropoiesis and vasculogenesis in vivo. | 27155222 |
| Type | IDs |
|---|---|
| Synonymous | 2900068C24Rik, Ddxbp1, GBP |
| Gene |
UniProtKB-ID:
PIAS1_MOUSE,
Q2M4G9_MOUSE
UniprotKB:
O88907,
Q2M4G9
UniParc:
UPI00000E9B38
EMBL:
BC051417,
AF077950,
AY902346,
AK075708
Ensembl:
ENSMUSG00000032405
KO:
mmu:56469
|
| Nucleutide sequences |
EMBL-CDS:
AAH51417.1,
BAC35902.1,
AAC36701.1,
AAY21056.1
Ensembl_TRS:
ENSMUST00000098651
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096248
RefSeq:
NP_062637.2,
XP_006511365.1
|
| Others |
UniRef100:
UniRef100_O88907
UniRef90:
UniRef90_O75925
UniRef50:
UniRef50_O75925
UniGene:
Mm.431253,
Mm.491651
CCDS:
CCDS40665.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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