| Type | Description |
|---|---|
| Definition | Kv channel interacting protein 3, calsenilin |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:07:00 | Proteomic Profile of a Chronic Binge Ethanol Exposure Model. | 31329447 |
| 2020-06-06 11:42:00 | These results suggest that DREAM and probably other members of the neuronal calcium sensor family bind Cd2+ with an affinity that is superior to that for Ca2+ and the interactions between toxic Cd2+ and DREAM and other neuronal calcium sensors provide novel insight into the molecular mechanism of Cd2+ neurotoxicity. | 31046050 |
| 2020-03-28 10:31:00 | Pb(2+) binds to EF-hands in apo-DREAM (downstream regulatory element antagonist modulator) with a lower equilibrium dissociation constant. Based on the Trp169 emission and CD spectra, Pb(2+) association triggers changes in the protein secondary and tertiary structures that are analogous to those previously observed for Ca(2+)-bound protein. | 30399317 |
| 2019-04-06 10:39:00 | calsenilin controls the activity of neuronal RyRs. | 29730765 |
| 2018-10-27 12:01:00 | DREAM inhibition markedly improves ATF6 processing in the hippocampus and that it might contribute to a delay in memory decline in Huntington mice. | 29523177 |
| Type | IDs |
|---|---|
| Synonymous | 4933407H12Rik, AI413860, Csen, DREAM, KChIP3, R74849 |
| Gene |
UniProtKB-ID:
CSEN_MOUSE,
A2AHT3_MOUSE,
Q3YAB0_MOUSE,
Q3YAA9_MOUSE
UniprotKB:
Q9QXT8,
A2AHT3,
Q3YAB0,
Q3YAA9
UniParc:
UPI00001EF982,
UPI00000E6E1C,
UPI000004A267,
UPI0000192FA9,
UPI000002861E
EMBL:
AF274050,
AF287734,
BC026980,
AF287733,
AF287736,
BC047139,
DQ148500,
DQ148499,
AL731831,
AF287732,
AF300870,
AF287737,
AF184624,
BC057329,
AF287735
Ensembl:
ENSMUSG00000079056
KO:
mmu:56461
|
| Nucleutide sequences |
EMBL-CDS:
AAG17450.1,
AAK08179.1,
AAH47139.1,
AAH57329.1,
AAF14576.1,
AAK08177.1,
AAH26980.1,
AAK08180.1,
AAF74784.1,
AAK08176.1,
AAK08175.1,
AAZ77816.1,
AAZ77817.1
Ensembl_TRS:
ENSMUST00000103215,
ENSMUST00000028850,
ENSMUST00000088538
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099504,
ENSMUSP00000028850,
ENSMUSP00000085896
RefSeq:
XP_011238012.1,
NP_062763.2,
NP_001104801.1,
NP_001277934.1
|
| Others |
UniRef100:
UniRef100_Q3YAA9,
UniRef100_A2AHT3,
UniRef100_Q9QXT8
UniRef90:
UniRef90_Q9Y2W7-3,
UniRef90_Q9QXT8,
UniRef90_P0C092
UniRef50:
UniRef50_Q9Y2W7-3,
UniRef50_Q9QXT8
UniGene:
Mm.315292
CCDS:
CCDS16703.1,
CCDS71139.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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