| Type | Description |
|---|---|
| Definition | dynein light chain LC8-type 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 11:46:00 | The authors discovered that the dissociation of the Dynll1-Cox4i1 complex is required for the release of mitochondrial reactive oxygen species and serves as a regulator of intracellular proliferation of Listeria monocytogenes. The study shows that Dynll1 is an inhibitor of mitochondrial reactive oxygen species. | 32041786 |
| 2017-10-14 11:38:00 | oncogenic MYC expression, which is synthetic lethal with Dynll1 deletion in B-2 cells, did not further reduce B-1a cell numbers in Dynll1-defcient mice. we found that the ASCIZ-DYNLL1 axis was also required for the early-juvenile development of aggressive MYC-driven and p53-deficient B cell lymphomas. | 28922373 |
| 2016-12-17 12:02:00 | ASCIZ and its target DYNLL1 are essential for the development and expansion of MYC-driven B cell lymphoma. | 26832406 |
| 2015-10-24 10:31:00 | These findings uncovered the surprising functional relevance of GTP-bound Arl3 and LC8 for the unloading regulation of dynactin-bound cargo from dynein motor. | 25342295 |
| 2012-11-17 10:24:00 | a key role for ASCIZ in regulating the survival of developing B cells by activating DYNLL1 expression, which may then modulate Bim-dependent apoptosis | 22891272 |
| Type | IDs |
|---|---|
| Synonymous | Dlc8, Dnclc1, Pin |
| Gene |
UniProtKB-ID:
DYL1_MOUSE
UniprotKB:
P63168
UniParc:
UPI0000000991
EMBL:
AK010614,
AK010685,
BC008106,
AK013721,
AK002522,
AK082923,
AK147977,
AF020185,
BC034258
Ensembl:
ENSMUSG00000009013
KO:
mmu:56455
|
| Nucleutide sequences |
EMBL-CDS:
AAH34258.1,
BAE28262.1,
BAB22160.1,
AAD01643.1,
AAH08106.1,
BAC38691.1,
BAB27117.1,
BAB27063.1,
BAB28970.1
Ensembl_TRS:
ENSMUST00000112090,
ENSMUST00000009157
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000107720,
ENSMUSP00000009157
RefSeq:
NP_062656.3
|
| Others |
UniRef100:
UniRef100_P63167
UniRef90:
UniRef90_P63167
UniRef50:
UniRef50_P63167
UniGene:
Mm.256858
CCDS:
CCDS39227.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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