| Type | Description |
|---|---|
| Definition | membrane-bound transcription factor peptidase, site 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-08-06 11:58:00 | Data (including data from studies in knockout mice) suggest osteocyte Mbtps1 expression is involved in development of sarcopenia in slow-twitch muscle fibers; Mbtps1 knockout mice (conditional osteocyte deletion) do not develop sarcopenia of aging. | 26719336 |
| 2016-04-30 10:22:00 | S1P substrate-dependent regulatory mechanisms for lipid synthesis and biogenesis of lysosomes are different | 26108224 |
| 2016-02-06 11:30:00 | A novel role for MBTPS1/SKI-1/S1P (membrane bound transcription factor protease, subtilisin kexin isozyme-1, or site 1 protease) in somite segmentation and in the pathogenesis of vertebral anomalies. | 25652402 |
| 2015-11-14 10:52:00 | These studies indicate an indispensable role for S1P in type IIB procollagen trafficking from the ER. | 25147951 |
| 2011-10-22 11:39:00 | Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice. | 21652717 |
| Type | IDs |
|---|---|
| Synonymous | 0610038M03Rik, AV003995, S1P, SKI-1, Ski1, mKIAA0091 |
| Gene |
UniProtKB-ID:
MBTP1_MOUSE
UniprotKB:
Q9WTZ2
UniParc:
UPI0000003F83
EMBL:
AF094820,
AK029048,
BC057198,
BC054837
Ensembl:
ENSMUSG00000031835
KO:
mmu:56453
|
| Nucleutide sequences |
EMBL-CDS:
BAC26263.1,
AAH57198.1,
AAH54837.1,
AAD27010.1
Ensembl_TRS:
ENSMUST00000098362,
ENSMUST00000081381
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095965,
ENSMUSP00000080117
RefSeq:
XP_011246753.1,
XP_011246752.1,
XP_011246751.1,
NP_062683.3,
XP_030099552.1,
NP_001161382.1,
XP_036010086.1,
XP_030099551.1
|
| Others |
UniRef100:
UniRef100_Q9WTZ2
UniRef90:
UniRef90_Q9WTZ2
UniRef50:
UniRef50_Q14703
UniGene:
Mm.206934
CCDS:
CCDS22707.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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