| Type | Description |
|---|---|
| Definition | sorting nexin 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 11:24:00 | Data suggest that both, N-terminal and C-terminal region of SNX1 play critical role in the normal trafficking of the group I metabotropic glutamate receptors (mGlur1). In addition, study shows that SNX1 regulates the trafficking of mGluR1 through the interaction with hepatocyte growth factor-regulated tyrosine kinase substrate. | 30143569 |
| 2014-05-17 15:40:00 | SNX1 interacts with Arf6 to mediate neurite formation which is regulated by EFA6A. | 24261326 |
| 2013-03-02 10:52:00 | SNX1 has a crucial role in D(5)R trafficking and SNX1 depletion results in D(5)R dysfunction and thus may represent a novel mechanism for the pathogenesis of essential hypertension | 23152498 |
| 2012-09-15 10:23:00 | A RUN Domain from DENND5/Rab6IP1 binds sorting Nexin 1 and is involved in the trafficking of vesicles at the level of Golgi. | 22558185 |
| 2010-01-21 00:00:00 | show that mice lacking sorting nexin 1 or sorting nexin 2 are viable and fertile, whereas embryos deficient in both proteins arrest at midgestation. | 12388759 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SNX1_MOUSE,
Q6NZD2_MOUSE
UniprotKB:
Q9WV80,
Q6NZD2
UniParc:
UPI0000028F81,
UPI000023B754
EMBL:
AF154120,
BC066189,
AK167177,
BC066044,
AC112676,
AK155746,
AK161241,
AB019214,
AK168742
Ensembl:
ENSMUSG00000032382
KO:
mmu:56440
|
| Nucleutide sequences |
EMBL-CDS:
BAB20283.1,
AAD38805.1,
AAH66044.1,
BAE39312.1,
BAE36261.1,
BAE40583.1,
AAH66189.1,
BAE33413.1
Ensembl_TRS:
ENSMUST00000034946
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034946
RefSeq:
NP_062701.2
|
| Others |
UniRef100:
UniRef100_Q6NZD2,
UniRef100_Q9WV80
UniRef90:
UniRef90_Q9WV80
UniRef50:
UniRef50_Q13596
UniGene:
Mm.271891
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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