| Type | Description |
|---|---|
| Definition | destrin |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 11:19:00 | Actin depolymerizing factor (ADF)/cofilin controls actin turnover to sustain axon regeneration after spinal cord injury through its actin-severing activity. This pinpoints ADF/cofilin as a key regulator of axon growth competence, irrespective of developmental stage. | 31400829 |
| 2018-07-14 10:05:00 | AGEs treatment increased endothelial permeability and reduced vasculogenic property of MBMECs, at least in part, via downregulation of ADF. | 28378130 |
| 2017-04-01 10:48:00 | Dstncorn1 mice are homozygous for a spontaneous null actin depolymerizing factor destrin (DSTN) allele, which results in an increase in serum response factor (Srf) expression.This study performs identification of functional pathways associated with the conditional ablation of serum response factor in Dstn corn1 mice. | 27922676 |
| 2016-03-12 11:17:00 | Actin depolymerizing factor/cofilin double mutant mice exhibited hyperlocomotion, impulsivity, and impaired working memory. Hyperlocomotion and impulsive behavior were reversed by methylphenidate. | 24768258 |
| 2014-12-20 10:45:00 | SRF binding is significantly decreased in the destrin (corn1) mutant cornea. | 24550211 |
| Type | IDs |
|---|---|
| Synonymous | 2610043P17Rik, ADF, AU042046, Dsn, corn1, sid23p |
| Gene |
UniProtKB-ID:
DEST_MOUSE,
Q4FK36_MOUSE
UniprotKB:
Q9R0P5,
Q4FK36
UniParc:
UPI0000004132
EMBL:
BC131926,
CT010216,
AK078898,
AB025406
Ensembl:
ENSMUSG00000015932
KO:
mmu:56431
|
| Nucleutide sequences |
EMBL-CDS:
BAA84691.1,
BAC37447.1,
CAJ18424.1,
AAI31927.1
Ensembl_TRS:
ENSMUST00000103172
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099461
RefSeq:
NP_062745.1
|
| Others |
UniRef100:
UniRef100_Q9R0P5
UniRef90:
UniRef90_P60981
UniRef50:
UniRef50_Q9Y281
UniGene:
Mm.28919
CCDS:
CCDS16812.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员