| Type | Description |
|---|---|
| Definition | programmed cell death 10 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. | 33495460 |
| 2020-10-10 13:01:00 | Mural Cell-Specific Deletion of Cerebral Cavernous Malformation 3 in the Brain Induces Cerebral Cavernous Malformations. | 32640906 |
| 2020-09-12 16:02:00 | Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. | 31776290 |
| 2017-08-12 10:21:00 | CCM3 suppresses UNC13B- and vesicle-associated membrane protein 3 (VAMP3)-dependent exocytosis of angiopoietin 2 (ANGPT2) in brain endothelial cells. CCM3 deficiency in endothelial cells augments the exocytosis and secretion of ANGPT2, which is associated with destabilized endothelial cell junctions, enlarged lumen formation and endothelial cell-pericyte dissociation. | 27548575 |
| 2016-08-06 11:12:00 | CCM3 expression and it's role during ovary and testis development | 26386873 |
| Type | IDs |
|---|---|
| Synonymous | 2410003B13Rik, Ccm3, Tfa15, Tfar15 |
| Gene |
UniProtKB-ID:
PDC10_MOUSE
UniprotKB:
Q8VE70
UniParc:
UPI0000022CF7
EMBL:
BC086778,
AK168857,
AK169689,
AK077308,
AF159368,
AK005594,
AK137198,
BC019650,
AK075926
Ensembl:
ENSMUSG00000027835
KO:
mmu:56426
|
| Nucleutide sequences |
EMBL-CDS:
AAH19650.1,
BAE23263.1,
AAH86778.1,
BAC36742.1,
BAC36058.1,
AAD44335.1,
BAB24143.1,
BAE41306.1,
BAE40678.1
Ensembl_TRS:
ENSMUST00000161137
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125752
RefSeq:
NP_062719.2
|
| Others |
UniRef100:
UniRef100_Q8VE70
UniRef90:
UniRef90_Q9BUL8
UniRef50:
UniRef50_Q9BUL8
UniGene:
Mm.316473
CCDS:
CCDS17414.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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