| Type | Description |
|---|---|
| Definition | protein phosphatase 4, catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 11:47:00 | The PP4 is indispensable for preventing DNA replication stress that could interfere with CSR, thereby promoting antibody switching during the humoral immune response. | 30237510 |
| 2017-05-20 10:58:00 | LCMT-1 homozygous knock-out MEFs exhibited hyperphosphorylation of HDAC3, a reported target of the methylation-dependent PP4R1-PP4c complex. Collectively, our data suggest that LCMT-1 coordinately regulates the carboxyl methylation of PP2A-related phosphatases and, consequently, their holoenzyme assembly and function. | 27507813 |
| 2017-01-14 10:08:00 | T cell-specific ablation of PP4 resulted in defective adaptive immunity, impaired T cell homeostatic expansion, and inefficient T cell proliferation. | 26940341 |
| 2016-11-12 11:45:00 | Data show that protein phosphatase 4 (PP4) is an important regulator in inflammatory related insulin resistance. | 26666849 |
| 2016-01-02 12:06:00 | Thus, serine/threonine phosphatase PP4 functions as a novel feedback negative regulator of RNA virus-triggered innate immunity. | 26363053 |
| Type | IDs |
|---|---|
| Synonymous | 1110002D08Rik, AU016079, PP-X, PP4C, Ppx, pp4 |
| Gene |
UniProtKB-ID:
PP4C_MOUSE,
Q3UNF2_MOUSE
UniprotKB:
P97470,
Q3UNF2
UniParc:
UPI0000023591
EMBL:
AF378669,
AK144244,
AF088911,
BC001993,
U79747
Ensembl:
ENSMUSG00000030697
KO:
mmu:56420
|
| Nucleutide sequences |
EMBL-CDS:
AAH01993.1,
AAC96297.1,
AAL35110.1,
AAB38494.1,
BAE25795.1
Ensembl_TRS:
ENSMUST00000206570,
ENSMUST00000032936
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146245,
ENSMUSP00000032936
RefSeq:
NP_062648.1,
XP_006508112.1,
NP_001347393.1
|
| Others |
UniRef100:
UniRef100_P60510
UniRef90:
UniRef90_P60510
UniRef50:
UniRef50_P60510
UniGene:
Mm.41998
CCDS:
CCDS21844.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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