| Type | Description |
|---|---|
| Definition | diaphanous related formin 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 12:05:00 | neuronal drebrin A directly interacts with mDia2 formin. | 30625038 |
| 2019-05-04 10:47:00 | The authors report that formins mDia1 and mDia2 dissociate faster under higher ionic strength and when actin concentration is increased. Profilin, known to increase the elongation rate of formin-associated filaments, surprisingly decreases the formin dissociation rate, by bringing formin FH1 domains in transient contact with the barbed end. | 29799413 |
| 2018-09-01 10:37:00 | These data identify Diaph3 as a major guard of cortical progenitors, unravel novel functions of Diaphanous formins and add insights into the pathobiology of microcephaly. | 27848932 |
| 2018-03-17 11:49:00 | mDia2 is regulated through acetylation and deacetylation at lysine 970 in the formin homology 2 domain | 28255013 |
| 2017-11-04 12:43:00 | findings add more complexity to the mDia2 activity cycle by showing that the open conformation may control actin dynamics also through actin-independent regulation of the proteasome | 27769112 |
| Type | IDs |
|---|---|
| Synonymous | 4930417P13Rik, Dia2, Diap3, Drf3, p134MDia2 |
| Gene |
UniProtKB-ID:
DIAP3_MOUSE
UniprotKB:
Q9Z207
UniParc:
UPI0000029711
EMBL:
AF094519
Ensembl:
ENSMUSG00000022021
KO:
mmu:56419
|
| Nucleutide sequences |
EMBL-CDS:
AAC71771.1
Ensembl_TRS:
ENSMUST00000168889
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129420
RefSeq:
XP_006519375.1,
XP_011243425.1,
NP_062644.1
|
| Others |
UniRef100:
UniRef100_Q9Z207
UniRef90:
UniRef90_Q9Z207
UniRef50:
UniRef50_Q9Z207
UniGene:
Mm.440585
CCDS:
CCDS36990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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