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56413 LTB4R2

56413

LTB4R2

leukotriene B4 receptor 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition leukotriene B4 receptor 2

研究结论

Date Results Publications
2019-09-28 11:53:00 The critical roles of BLT2 on the functions of bronchial epithelial cells. 29323699
2019-09-14 13:19:00 Authors found that BLT2, a cell surface GPCR for leukotriene B4 and 12hydroxyeicosatetraenoic acid, is highly upregulated in KRAS mutant LOVO and SW480 colorectal cancer cells and plays critical roles in mediating proliferation through activation of phosphatidylinositol 3kinase (PI3K)/protein kinase B (Akt) and subsequent upregulation of cyclin D1. 30553812
2019-03-09 11:44:00 Our analysis identified six significant (Sidak corrected P < 0.05) depression-associated differentially methylated regions (DMRs); the top-ranked DMR was located in exon 1 of the LTB4R2 gene (Sidak corrected P = 1.27 x 10-14). 29790996
2018-10-20 12:21:00 In a group of 545 breast cancer patients with metastasis, authors observed that the high-BLT2 subgroup had a lower disease-free-survival rate than the low-BLT2 subgroup. 29898809
2018-08-25 10:47:00 BLT2 gene polymorphism (D196G) enhances ligand sensitivity, thereby increasing cell motility in response to low-dose ligand stimulation. 29170475

名称对应

Type IDs
Synonymous BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
Gene
UniProtKB-ID: LT4R2_HUMAN, B4E292_HUMAN
UniprotKB: Q9NPC1, B4E292
UniParc: UPI00017A86CB, UPI000003C105
EMBL: AB032558, AJ278605, AB083604, AF277230, AB044402, AB029892, AL096870, AB008193, AY268433, CH471078, AF308571, AK304169
Ensembl: ENSG00000213906, ENSG00000285203
KO: hsa:56413
Nucleutide sequences
EMBL-CDS: EAW66030.1, BAA99553.1, BAB00610.1, BAD83590.1, AAF81261.1, BAB89317.1, AAG40857.1, AAP23200.1, CAB96134.1, BAA99539.1, BAG65054.1
Ensembl_TRS: ENST00000533293, ENST00000644309, ENST00000643080, ENST00000543919
Protein sequencees
Ensembl_PRO: ENSP00000494877, ENSP00000494694, ENSP00000433290, ENSP00000445772
RefSeq: NP_001158164.1, NP_062813.2
Others
UniRef100: UniRef100_Q9NPC1, UniRef100_B4E292
UniRef90: UniRef90_A0A286XSG6, UniRef90_Q9NPC1
UniRef50: UniRef50_Q9NPC1
UniGene: Hs.642693, Hs.657595
CCDS: CCDS9625.2

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