| Type | Description |
|---|---|
| Definition | nuclear receptor coactivator 6 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:37:00 | PRIP deficiency impairs osteoclast differentiation, particularly at the early stages, and PRIP stimulates osteoclast differentiation through calcium-calcineurin-NFATc1 signaling via regulating intracellular Ca(2+) | 28341745 |
| 2017-07-08 10:06:00 | The results suggest that NCOA6 stimulates insulin secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells. | 28435063 |
| 2016-08-13 10:18:00 | These results indicate that PRIP is implicated in BMP-induced osteoblast differentiation by the negative regulation of Smad phosphorylation, through the methylation of inhibitory Smad6. | 25981537 |
| 2016-07-16 11:29:00 | The results indicate that PRIP negatively regulates UCP1-mediated thermogenesis in brown adipocytes. | 26706316 |
| 2015-05-30 13:54:00 | Two independent mouse models of NCOA6 dysfunction develop severe dilated cardiomyopathy with impaired mitochondrial function and reduced activity of peroxisome proliferator-activated receptor delta. | 25131203 |
| Type | IDs |
|---|---|
| Synonymous | AIB3, ASC-2, ASC2, NRC, Ncoa7, PRIP, RAP250, mKIAA0181 |
| Gene |
UniProtKB-ID:
Q5XJV5_MOUSE,
F6M2J9_MOUSE
UniprotKB:
Q5XJV5,
F6M2J9
UniParc:
UPI00001EE380,
UPI0000193A90
EMBL:
BC083187,
AL844852,
JF707634,
AL845325
Ensembl:
ENSMUSG00000038369
KO:
mmu:56406
|
| Nucleutide sequences |
EMBL-CDS:
AAH83187.1,
AEG79561.1
Ensembl_TRS:
ENSMUST00000043126,
ENSMUST00000109670
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105295,
ENSMUSP00000045386
RefSeq:
XP_011238011.1,
NP_001229487.1,
XP_006499991.1,
XP_011238010.1,
NP_062799.2,
XP_006499990.1
|
| Others |
UniRef100:
UniRef100_Q5XJV5,
UniRef100_F6M2J9
UniRef90:
UniRef90_F6M2J9,
UniRef90_Q5XJV5
UniRef50:
UniRef50_K7GF37,
UniRef50_Q14686
UniGene:
Mm.27592
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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