| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 14 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:09:00 | Results indicate that dual specificity phosphatase 14 (Dusp14) as an important molecular switch resulting in osteoporosis through an protein kinase AMP-activated alpha 1 catalytic subunit (AMPKalpha)-dependent manner. | 31526569 |
| 2019-11-09 10:23:00 | DUSP14 up-regulation inhibits inflammation and oxidative stress in brain of cerebral ischemia/reperfusion mice. DUSP14 evokes Nrf-2-meditated anti-oxidative stress and inflammatory response. | 30638656 |
| 2018-10-13 11:58:00 | Hepatocyte DUSP14 is required for maintaining hepatic metabolic homeostasis and for suppressing inflammation, a novel function that relies on constraining TAK1 hyperactivation | 29077210 |
| 2018-10-13 11:36:00 | DUSP14-knockdown in primary cardiomyocytes using its specific siRNA sequence elevated hypoxia and reoxygenation-induced activation of NF-kappaB and MAPKs signaling pathways, and reactive oxygen species generation. | 29660332 |
| 2016-10-22 11:26:00 | protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction possibly through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway | 26891723 |
| Type | IDs |
|---|---|
| Synonymous | 1110014C10Rik, 2310042C07Rik, D11Ertd395e, MKP-L, Mkp6 |
| Gene |
UniProtKB-ID:
DUS14_MOUSE,
Q542U4_MOUSE
UniprotKB:
Q9JLY7,
Q542U4
UniParc:
UPI0000004139
EMBL:
BC002130,
AF120113,
AK079362,
AK009744,
AK166840
Ensembl:
ENSMUSG00000018648
KO:
mmu:56405
|
| Nucleutide sequences |
EMBL-CDS:
BAB26474.1,
AAF28862.1,
AAH02130.1,
BAE39062.1,
BAC37622.1
Ensembl_TRS:
ENSMUST00000018792,
ENSMUST00000100705,
ENSMUST00000108101,
ENSMUST00000164891
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018792,
ENSMUSP00000098271,
ENSMUSP00000130624,
ENSMUSP00000103736
RefSeq:
XP_006533861.1,
XP_006533862.1,
XP_036012759.1,
XP_006533859.1,
NP_062793.2,
XP_006533860.1
|
| Others |
UniRef100:
UniRef100_Q9JLY7
UniRef90:
UniRef90_Q9JLY7
UniRef50:
UniRef50_Q9JLY7
UniGene:
Mm.240885,
Mm.475342
CCDS:
CCDS25182.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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