| Type | Description |
|---|---|
| Definition | prolyl 3-hydroxylase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 11:18:00 | P3H1 deficiency leads to decreased deposition of extracellular matrix by osteoblasts and increased incorporation of mineral into the matrix. | 26808442 |
| 2014-06-21 13:01:00 | we generated knock-in mice carrying a single amino acid substitution in the catalytic site of P3h1 (Lepre1(H662A) ). This substitution abolished P3h1 activity but retained ability to form a complex with Crtap and thus the collagen chaperone | 24465224 |
| 2014-01-04 13:17:00 | An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro. | 24043621 |
| 2013-11-16 10:04:00 | The absence of 3-hydroxyproline and/or the increased glycosylation of hydroxylysine in type I collagen disturbs the lateral growth of the fibrils. | 23861401 |
| 2013-07-27 12:26:00 | The LEPRE1 knockout mouse is a valuable model system to investigate the mechanism of hearing loss in recessive osteogenesis imperfecta. | 23186870 |
| Type | IDs |
|---|---|
| Synonymous | 2410024C15Rik, Gros1, Lepre1 |
| Gene |
UniProtKB-ID:
P3H1_MOUSE,
A6PW84_MOUSE,
A2A7Q5_MOUSE
UniprotKB:
Q3V1T4,
A6PW84,
A2A7Q5
UniParc:
UPI00001F13EA,
UPI0000D89842,
UPI0001574854,
UPI0000D89843,
UPI000059E0BD
EMBL:
AK132262,
BC024047,
AF165163,
AK159505,
AL606975,
AF165164,
AK010578,
AK030436
Ensembl:
ENSMUSG00000028641
KO:
mmu:56401
|
| Nucleutide sequences |
EMBL-CDS:
BAB27041.1,
BAC26962.1,
BAE21065.1,
AAF04807.1,
BAE35138.1,
AAF04806.1,
AAH24047.1
Ensembl_TRS:
ENSMUST00000121111,
ENSMUST00000081606,
ENSMUST00000030393,
ENSMUST00000102662
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000112504,
ENSMUSP00000080312,
ENSMUSP00000030393,
ENSMUSP00000099723
RefSeq:
NP_001035874.1,
NP_062757.2,
NP_001273077.1,
NP_062756.2
|
| Others |
UniRef100:
UniRef100_A6PW84,
UniRef100_A2A7Q5,
UniRef100_Q3V1T4
UniRef90:
UniRef90_Q3V1T4
UniRef50:
UniRef50_Q32P28
UniGene:
Mm.27961
CCDS:
CCDS38859.1,
CCDS38860.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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