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56379 Kcnj1

56379

Kcnj1

potassium inwardly-rectifying channel, subfamily J, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium inwardly-rectifying channel, subfamily J, member 1

研究结论

Date Results Publications
2021-01-23 13:00:00 Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP. 32004507
2019-07-13 10:59:00 WNK1, but not WNK4, is required for high potassium intake-induced stimulation of ROMK activity in convoluted kidney tubules. 29667910
2019-01-19 11:47:00 ROMK is expressed in the urinary tract at both protein and mRNA levels. Significant enlargement and hypertrophy of the bladder may contribute to hydronephrosis in male ROMK KO mice. 29092859
2017-09-23 14:08:00 The results provide evidence that NHERF1 mediates K(+) current activity through acceleration of the surface expression of ROMK1 K(+) channels in M-1 cells. 28533091
2017-07-15 10:37:00 ENaC and ROMK channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4(PHAII)-induced inhibition of ENaC and ROMK may contribute to the suppression of K(+) secretion in the tubules. 28365586

名称对应

Type IDs
Synonymous Kir1.1, ROMK, Romk2
Gene
UniProtKB-ID: KCNJ1_MOUSE, G3UWE7_MOUSE
UniprotKB: O88335, G3UWE7
UniParc: UPI000000199A, UPI00001F71CB
EMBL: AF012834, BC020525, AC132114
Ensembl: ENSMUSG00000041248
KO: mmu:56379
Nucleutide sequences
EMBL-CDS: AAH20525.1, AAC24973.1
Ensembl_TRS: ENSMUST00000047334, ENSMUST00000213393, ENSMUST00000172015
Protein sequencees
Ensembl_PRO: ENSMUSP00000150540, ENSMUSP00000046793, ENSMUSP00000131625
RefSeq: NP_062633.1, NP_001161826.1
Others
UniRef100: UniRef100_G3UWE7, UniRef100_O88335
UniRef90: UniRef90_P35560
UniRef50: UniRef50_P48048
UniGene: Mm.390168
CCDS: CCDS22953.1

全选

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