| Type | Description |
|---|---|
| Definition | fizzy and cell division cycle 20 related 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:28:00 | Oocytes mount a noncanonical DNA damage response involving APC-Cdh1-mediated proteolysis. | 32328643 |
| 2019-12-14 12:03:00 | Cdh1 suppresses the kinase activity of c-Src in an anaphase promoting complex-independent manner. Depleting Cdh1 accelerates breast cancer cell proliferation and cooperates with PTEN loss to promote breast tumor progression in mice. Findings reveal a reciprocal feedback circuit of Cdh1 and c-Src in the crosstalk between the cell cycle machinery and the c-Src signaling pathway. | 31420536 |
| 2018-07-16 16:46:00 | Both catalytic and non-catalytic APC/C-Fzr1/Cdh1-mediated activities of PTEN are required for stalk cells' proliferative arrest. Findings implicate the PTEN-APC/C-Fzr1/Cdh1 hub in angiogenesis. | 26228240 |
| 2018-07-16 16:40:00 | This is the first report revealing Cdh1 function in adult hematopoiesis and showing a role of Cdh1 in a G2/M checkpoint regulation in vivo | 21255192 |
| 2018-07-16 16:31:00 | Cdh1 is required to prevent the accumulation of cyclin B1 in terminally differentiated neurons. | 16148219 |
| Type | IDs |
|---|---|
| Synonymous | AW108046, Cdh1, FZR, FZR2, Fyr, HCDH, HCDH1 |
| Gene |
UniProtKB-ID:
FZR1_MOUSE,
Q3U3D4_MOUSE
UniprotKB:
Q9R1K5,
Q3U3D4
UniParc:
UPI0000021882
EMBL:
BC006616,
AK154822,
AF083809
Ensembl:
ENSMUSG00000020235
KO:
mmu:56371
|
| Nucleutide sequences |
EMBL-CDS:
AAH06616.1,
AAD52029.1,
BAE32854.1
Ensembl_TRS:
ENSMUST00000140901
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114203
RefSeq:
NP_062731.1
|
| Others |
UniRef100:
UniRef100_Q9R1K5
UniRef90:
UniRef90_Q9R1K5
UniRef50:
UniRef50_Q9R1K5
UniGene:
Mm.24202
CCDS:
CCDS24057.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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