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56365 Clcnkb

56365

Clcnkb

chloride channel, voltage-sensitive Kb

protein-coding

Mus musculus

基因描述

Type Description
Definition chloride channel, voltage-sensitive Kb

研究结论

Date Results Publications
2018-07-06 16:40:00 Loss of ClC-K2 compromises TAL function and abolishes salt reabsorption in the distal convoluted tubule. Our data suggest that ClC-K2 is crucial for renal salt reabsorption and concentrating ability. ClC-K2-deficient mice in most aspects mimic patients with Bartter's syndrome type 3. 27421685
2017-11-11 10:41:00 Through the combined effects of pHi and pHo on ClC-K2, might be a key regulator of NaCl absorption. 27574292
2015-03-21 13:21:00 IGF-1, by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the cortical collecting duct. 25339702

名称对应

Type IDs
Synonymous CLCKB, Clc-Ka, Clck2, Clcnk1l, Clcnk2
Gene
UniProtKB-ID: CLCKB_MOUSE
UniprotKB: Q9WUB6
UniParc: UPI000059E1E0, UPI0000020F46
EMBL: BC019983, AL670285, CH466615, AF124847
Ensembl: ENSMUSG00000006216
KO: mmu:56365
Nucleutide sequences
EMBL-CDS: AAD21082.1, AAH19983.1, EDL13372.1
Ensembl_TRS: ENSMUST00000105788, ENSMUST00000006378
Protein sequencees
Ensembl_PRO: ENSMUSP00000101414, ENSMUSP00000006378
RefSeq: XP_011248609.1, XP_006539131.1, XP_006539130.1, NP_062675.2, XP_006539129.1
Others
UniRef100: UniRef100_Q9WUB6
UniRef90: UniRef90_P51802
UniRef50: UniRef50_P51802
UniGene: Mm.24882
CCDS: CCDS18872.1

全选

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研究热度

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