Type | Description |
---|---|
Definition | chloride channel, voltage-sensitive Kb |
Date | Results | Publications |
---|---|---|
2018-07-06 16:40:00 | Loss of ClC-K2 compromises TAL function and abolishes salt reabsorption in the distal convoluted tubule. Our data suggest that ClC-K2 is crucial for renal salt reabsorption and concentrating ability. ClC-K2-deficient mice in most aspects mimic patients with Bartter's syndrome type 3. | 27421685 |
2017-11-11 10:41:00 | Through the combined effects of pHi and pHo on ClC-K2, might be a key regulator of NaCl absorption. | 27574292 |
2015-03-21 13:21:00 | IGF-1, by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the cortical collecting duct. | 25339702 |
Type | IDs |
---|---|
Synonymous | CLCKB, Clc-Ka, Clck2, Clcnk1l, Clcnk2 |
Gene |
UniProtKB-ID:
CLCKB_MOUSE
UniprotKB:
Q9WUB6
UniParc:
UPI000059E1E0,
UPI0000020F46
EMBL:
BC019983,
AL670285,
CH466615,
AF124847
Ensembl:
ENSMUSG00000006216
KO:
mmu:56365
|
Nucleutide sequences |
EMBL-CDS:
AAD21082.1,
AAH19983.1,
EDL13372.1
Ensembl_TRS:
ENSMUST00000105788,
ENSMUST00000006378
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101414,
ENSMUSP00000006378
RefSeq:
XP_011248609.1,
XP_006539131.1,
XP_006539130.1,
NP_062675.2,
XP_006539129.1
|
Others |
UniRef100:
UniRef100_Q9WUB6
UniRef90:
UniRef90_P51802
UniRef50:
UniRef50_P51802
UniGene:
Mm.24882
CCDS:
CCDS18872.1
|
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