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56341 PRMT8

56341

PRMT8

protein arginine methyltransferase 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein arginine methyltransferase 8

研究结论

Date Results Publications
2018-05-05 10:17:00 PRMT8 in human embryonic stem cells plays an important role not only in maintaining pluripotency but also in controlling mesodermal differentiation. 28543863
2016-08-20 11:43:00 Biochemical, biophysical and mutagenesis experiments demonstrated that hPRMT8 forms an octamer in solution. 26876602
2014-01-18 10:44:00 Mutational defects in PRMT8 is not the cause of frontotemporal lobar degeneration. 23635657
2013-12-28 10:44:00 automethylation of the N terminus likely regulates PRMT8 activity by decreasing the affinity of the enzyme for AdoMet 23946480
2013-11-16 11:15:00 wild type FUS (FUS-WT) specifically interacts with protein arginine methyltransferases 1 and 8 (PRMT1 and PRMT8) and undergoes asymmetric dimethylation 23620769

名称对应

Type IDs
Synonymous HRMT1L3, HRMT1L4
Gene
UniProtKB-ID: ANM8_HUMAN, Q59GT2_HUMAN
UniprotKB: Q9NR22, Q59GT2
UniParc: UPI0000E22F84, UPI00004F6B3D, UPI00005B2E00
EMBL: AC005908, AC005831, AF263539, AC005925, BC022458, AB209027, AK315619
Ensembl: ENSG00000111218
KO: hsa:56341
Nucleutide sequences
EMBL-CDS: AAF91390.1, AAH22458.2, BAG37987.1, BAD92264.1
Ensembl_TRS: ENST00000452611, ENST00000382622
Protein sequencees
Ensembl_PRO: ENSP00000414507, ENSP00000372067
RefSeq: XP_016875133.1, XP_016875134.1, NP_001243465.1, NP_062828.3, XP_024304827.1
Others
UniRef100: UniRef100_Q59GT2, UniRef100_Q9NR22
UniRef90: UniRef90_Q9NR22, UniRef90_Q59GT2
UniRef50: UniRef50_A0A287BTE0, UniRef50_Q9NR22
UniGene: Hs.504530
CCDS: CCDS8521.2, CCDS58200.1

全选

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