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56315 Rhcg

56315

Rhcg

Rhesus blood group-associated C glycoprotein

protein-coding

Mus musculus

基因描述

Type Description
Definition Rhesus blood group-associated C glycoprotein

研究结论

Date Results Publications
2018-12-22 12:31:00 RhCG and H+ATPases are located within the same cellular protein complex in the kidney and this interaction is required for maximal urinary acidification by H+-ATPases, a prerequisite for efficient NH3 secretion and urine excretion of NH4+. 29054531
2015-12-10 17:56:00 We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)). 26354748
2014-11-22 12:30:00 investigated the renal adaptive response of acid excretory pathways to high-protein diets containing normal or low amounts of acid-producing sulfur amino acids (SAA) and examined how this adaption requires the RhCG ammonia transporter 24652796
2014-07-19 11:43:00 Rh B Glycoprotein (Rhbg) and Rh C Glycoprotein (Rhcg) are identified as ammonia transporters. They are expressed in specific cell populations and membrane domains in distal renal epithelial cells, where they facilitate ammonia secretion. 24647713
2014-05-03 11:27:00 Rhcg is critically important in the renal response to metabolic acidosis. in mice with intact Rhcg expression, metabolic acidosis does not induce maximal changes in PEPCK, NHE-3, and GS expression despite the presence of persistent metabolic acidosis. 24338819

名称对应

Type IDs
Synonymous BB065800
Gene
UniProtKB-ID: RHCG_MOUSE
UniprotKB: Q9QXP0
UniParc: UPI0000023523
EMBL: AK076757, BC119045, AF193810, AY254686
Ensembl: ENSMUSG00000030549
KO: mmu:56315
Nucleutide sequences
EMBL-CDS: BAC36469.1, AAI19046.1, AAF19373.1, AAP81168.1
Ensembl_TRS: ENSMUST00000032766
Protein sequencees
Ensembl_PRO: ENSMUSP00000032766
RefSeq: NP_062773.2, XP_006541067.1, XP_011249180.1
Others
UniRef100: UniRef100_Q9QXP0
UniRef90: UniRef90_Q9QXP0
UniRef50: UniRef50_Q9QXP0
UniGene: Mm.10909
CCDS: CCDS21383.1

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