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56310 Gps2

56310

Gps2

G protein pathway suppressor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition G protein pathway suppressor 2

研究结论

Date Results Publications
2021-03-20 13:35:00 The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages. 33503407
2021-02-20 13:32:00 GPS2 promotes erythroid differentiation by control of the stability of EKLF protein. 32384137
2019-07-13 11:24:00 GPS2 enhances BK channel activity and its protein expression by reducing ERK1/2 signaling-mediated degradation of the channel. 29767559
2019-05-11 10:55:00 Study in GPS2 knockout mice reveals that GPS2 in hepatocytes functionally cooperates with NCOR but not with SMRT to repress PPAR-alpha. These data collectively suggest that GPS2 promotes the progression of fatty liver disease as an epigenome modifier and PPAR-alpha-selective corepressor in hepatocytes. 30975991
2019-01-05 10:23:00 These findings, together, reveal an additional layer of regulation of mitochondrial gene transcription, uncover a direct mitochondria-nuclear communication pathway, and indicate that GPS2 retrograde signaling is a key component of the mitochondrial stress response in mammals. 29499132

名称对应

Type IDs
Synonymous AI505953, GPS-2
Gene
UniProtKB-ID: GPS2_MOUSE
UniprotKB: Q921N8
UniParc: UPI00000220F3
EMBL: BC011317, BC138879, AL596185, CH466596, BC138880
Ensembl: ENSMUSG00000023170
KO: mmu:56310
Nucleutide sequences
EMBL-CDS: AAI38881.1, AAI38880.1, AAH11317.1, EDL12474.1, EDL12472.1
Ensembl_TRS: ENSMUST00000057884, ENSMUST00000072581, ENSMUST00000116358
Protein sequencees
Ensembl_PRO: ENSMUSP00000054072, ENSMUSP00000112062, ENSMUSP00000072389
RefSeq: NP_062700.2, XP_030102047.1, NP_001344835.1
Others
UniRef100: UniRef100_Q921N8
UniRef90: UniRef90_Q921N8
UniRef50: UniRef50_Q13227-2
UniGene: Mm.477738
CCDS: CCDS24922.1

全选

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研究热度

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