| Type | Description |
|---|---|
| Definition | phosphoribosyl pyrophosphate synthetase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:25:00 | A novel mutation in gene of PRPS1 in a young Chinese woman with X-linked gout: a case report and review of the literature. | 31773495 |
| 2020-05-30 12:29:00 | High PRPS1 expression is associated with colorectal cancer. | 31253668 |
| 2020-05-30 12:18:00 | CMTX5 is probably under-diagnosed, as an overlap among the different features due to PRPS1 exists. Patients who developed polyneuropathy associated to sensorineural deafness and optic atrophy during childhood should be assessed for | 31338985 |
| 2019-11-02 10:54:00 | Our study not only provides mechanistic rationale for re-targeting drug resistant cells in acute lymphoblastic leukemia (ALL), but also implicates that ALL patients who harbor relapse-specific mutations of PRPS1 might benefit from 5-FU-based chemotherapy in clinical settings. | 30255549 |
| 2019-03-30 11:41:00 | PRPS1 protein and transcript levels are detected as significantly decreased in cell lines derived from the Hutchinson-Gilford progeria syndrome patients. | 30379953 |
| Type | IDs |
|---|---|
| Synonymous | ARTS, CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI |
| Gene |
UniProtKB-ID:
PRPS1_HUMAN,
A0A0A0MRQ9_HUMAN,
B7ZB02_HUMAN
UniprotKB:
P60891,
A0A0A0MRQ9,
B7ZB02
UniParc:
UPI0016301298,
UPI0001915332,
UPI00000000A5,
UPI00005ABAA6
EMBL:
AL772400,
AK312706,
CH471120,
X15331,
AL137787,
AK297968,
BC001605,
D00860,
AK316467
Ensembl:
ENSG00000147224
KO:
hsa:5631
|
| Nucleutide sequences |
EMBL-CDS:
EAX02709.1,
BAG35584.1,
CAA33386.1,
EAX02711.1,
EAX02710.1,
BAG60278.1,
AAH01605.1,
BAA00733.1,
BAH14838.1
Ensembl_TRS:
ENST00000372435,
ENST00000372428
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361512,
ENSP00000361505
RefSeq:
NP_002755.1,
NP_001191331.1
|
| Others |
UniRef100:
UniRef100_P60891,
UniRef100_L9L7D1,
UniRef100_A0A0A0MRQ9
UniRef90:
UniRef90_P60891,
UniRef90_L9L7D1,
UniRef90_A0A0A0MRQ9
UniRef50:
UniRef50_L9L7D1,
UniRef50_A0A0A0MRQ9,
UniRef50_P60891
UniGene:
Hs.56
CCDS:
CCDS14529.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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