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56305 Pitpnb

56305

Pitpnb

phosphatidylinositol transfer protein, beta

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphatidylinositol transfer protein, beta

研究结论

Date Results Publications
2019-07-20 12:52:00 these data show that ablating PITPs in MKs indirectly dysregulates hematopoiesis in the BM by disrupting alpha-granule physiology and secretion of TGF-beta1. 30042096
2010-01-21 00:00:00 Data suggest that phosphatidylinositol transfer protein (PITP) beta is an essential housekeeping PITP in murine cells, whereas PITP alpha plays a far more specialized function in mammals. 11907258
2010-01-21 00:00:00 The PITPbeta deficiency results in catastrophic failure early in murine embryonic development, and the PITPbeta is an essential housekeeping PIPT in murine cells. 15052341
2010-01-21 00:00:00 PITPbeta localizes predominantly to the trans-Golgi network (TGN) and that this localization is independent of the phospholipid-bound state of PITPbeta. 16540520
2010-01-21 00:00:00 The Golgi localization of phosphatidylinositol transfer protein beta requires the protein kinase C-dependent phosphorylation of serine 11953429

名称对应

Type IDs
Synonymous PI-TP-beta
Gene
UniProtKB-ID: PIPNB_MOUSE, Q8JZZ5_MOUSE
UniprotKB: P53811, Q8JZZ5
UniParc: UPI0000003F5F, UPI00000E5AAD
EMBL: BC034676, AC122226, AK028235, U46934
Ensembl: ENSMUSG00000050017
KO: mmu:56305
Nucleutide sequences
EMBL-CDS: AAA87593.1, BAC25830.1, AAH34676.1
Ensembl_TRS: ENSMUST00000086635, ENSMUST00000200298
Protein sequencees
Ensembl_PRO: ENSMUSP00000083835, ENSMUSP00000142732
RefSeq: NP_001288572.1, NP_001346146.1, NP_062614.1, NP_001288573.1, NP_001288595.1, NP_001346144.1, NP_001346145.1
Others
UniRef100: UniRef100_Q8JZZ5, UniRef100_P53811
UniRef90: UniRef90_P53811
UniRef50: UniRef50_P53811
UniGene: Mm.200516, Mm.474970
CCDS: CCDS39213.1

全选

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