| Type | Description |
|---|---|
| Definition | par-3 family cell polarity regulator |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:50:00 | Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death. | 32328642 |
| 2020-08-12 10:53:00 | The current study demonstrates that the SLCO4A1-AS1/miR-508-3p/PARD3/autophagy pathway play a critical role in colorectal cancer cell proliferatio | 31308265 |
| 2020-07-04 11:34:00 | these findings identify RhoA as a novel target of Pard3 in gliomas and substantiate a novel regulatory role for Pard3 in glioma progression. | 30848088 |
| 2020-03-21 10:18:00 | The authors report here that the homophilic receptor PTPRK is stabilized at cell-cell contacts in epithelial cells. PTPRK directly and selectively dephosphorylates at least five substrates, including Afadin, PARD3 and delta-catenin family members, which are all important cell-cell adhesion regulators. | 30924770 |
| 2019-06-08 11:12:00 | PAR-3 controls microtubule stability via inhibition of GSK3beta in a dose-dependent manner. The dose-dependent effect of PAR-3 on GSK3beta phosphorylation is due to antagonism between the and the complexes. | 30018153 |
| Type | IDs |
|---|---|
| Synonymous | ASIP, Baz, PAR3, PAR3alpha, PARD-3, PARD3A, PPP1R118, SE2-5L16, SE2-5LT1, SE2-5T2 |
| Gene |
UniProtKB-ID:
PARD3_HUMAN
UniprotKB:
Q8TEW0
UniParc:
UPI0000073AFD,
UPI00000706A6,
UPI000006FD1C,
UPI0000073A9F,
UPI0001D3414C,
UPI0000073CCD,
UPI000006D8C0,
UPI0000071BC4,
UPI000004D1FB,
UPI000019B504,
UPI0000073252
EMBL:
AL392123,
AF467005,
AL390766,
AF177228,
AF196185,
AF196186,
AK000761,
AL360233,
AL138768,
AL450337,
AF467004,
AF332592,
CH471072,
AB073671,
BC071566,
AK027735,
AF467002,
BC011711,
AF252293,
AF467006,
AF467003,
AL160409,
AF332593
Ensembl:
ENSG00000148498
KO:
hsa:56288
|
| Nucleutide sequences |
EMBL-CDS:
AAH71566.1,
AAK27891.1,
AAL76042.1,
AAK69192.1,
AAL76044.1,
BAB55330.1,
EAW85932.1,
AAK27892.1,
AAL76045.1,
AAK69193.1,
AAL76043.1,
AAL76046.1,
AAF71530.1,
AAH11711.2,
AAG33676.1,
BAA91366.1,
BAC54037.1,
EAW85934.1
Ensembl_TRS:
ENST00000374788,
ENST00000545693,
ENST00000346874,
ENST00000374776,
ENST00000340077,
ENST00000350537,
ENST00000374789,
ENST00000374794,
ENST00000545260
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363921,
ENSP00000443147,
ENSP00000340591,
ENSP00000363908,
ENSP00000363920,
ENSP00000341844,
ENSP00000440857,
ENSP00000311986,
ENSP00000363926
RefSeq:
NP_001171720.1,
NP_001171716.1,
NP_001171715.1,
NP_001171714.1,
NP_001171717.1,
NP_001171723.1,
NP_001171718.1,
NP_001171721.1,
NP_001171722.1,
NP_001171719.1,
NP_062565.2
|
| Others |
UniRef100:
UniRef100_Q8TEW0
UniRef90:
UniRef90_Q8TEW0
UniRef50:
UniRef50_Q8TEW0
UniGene:
Hs.131489
CCDS:
CCDS53511.1,
CCDS53516.1,
CCDS53513.1,
CCDS53509.1,
CCDS7178.1,
CCDS53515.1,
CCDS53510.1,
CCDS53512.1,
CCDS53514.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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