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56287 GKN1

56287

GKN1

gastrokine 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition gastrokine 1

研究结论

Date Results Publications
2020-10-24 14:10:00 Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer. 32538140
2020-08-22 15:31:00 The diagnostic value of serum gastrokine 1 (GKN1) protein in gastric cancer. 31376239
2020-05-30 11:52:00 AUF1 knockdown resulted in upregulation of GKN1 expression and promoted GKN1 mRNA decay by binding the 3' untranslated region of GKN1 mRNA H. pylori-induced AUF1 expression was associated with p-ERK activation and CagA. 31657090
2020-02-08 12:39:00 GKN1 plays an important role in the maintenance of gastric homeostasis. In inflamed mucosa, both with and without H. pylori infection, GKN1 levels decrease, while the protein is absent in gastric cancer. The measurement of circulating GKN1 concentration, the protein itself or its mRNA in gastric tissue could be useful for the early diagnosis of cancer. [review] 31322194
2020-02-01 10:47:00 K14-high cells contribute to lung cancer metastasis potentially through inhibition of anoikis via upregulation of Gkn1. 31320708

名称对应

Type IDs
Synonymous AMP18, BRICD1, CA11, FOV, foveolin
Gene
UniProtKB-ID: GKN1_HUMAN, Q53YU7_HUMAN
UniprotKB: Q9NS71, Q53YU7
UniParc: UPI00000359F1, UPI0000126BA7
EMBL: AY139184, AJ966789, AC114802, AB039886, AY456961, BC059778, AY359050, AY139182
Ensembl: ENSG00000169605
KO: hsa:56287
Nucleutide sequences
EMBL-CDS: AAN75449.1, AAH59778.2, AAN75447.1, BAA92433.1, AAQ89409.1, CAI85015.1, AAR21211.1, AAY24066.1
Gene_ORFName: UNQ489/PRO1005
Ensembl_TRS: ENST00000673932, ENST00000377938
Protein sequencees
Ensembl_PRO: ENSP00000501093, ENSP00000367172
RefSeq: NP_062563.4
Others
UniRef100: UniRef100_Q9NS71
UniRef90: UniRef90_Q9NS71
UniRef50: UniRef50_Q9NS71
UniGene: Hs.69319

全选

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