| Type | Description |
|---|---|
| Definition | brain expressed X-linked 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | Aberrant brain-expressed X-linked 4 (BEX4) expression is a novel prognostic biomarker in gastric cancer. | 33217815 |
| 2019-06-01 12:00:00 | these results suggest that the oncogenicity of BEX4 is conferred by PLK1-mediated phosphorylation, and thus, the BEX4-PLK1 interaction is a novel oncogenic signal that enables the acquisition of chromosomal aneuploidy. | 30367032 |
| 2018-09-22 11:48:00 | BEX4 positively regulated the expression of OCT4, silencing of which reduced the proliferation of A549 and H1975cells with over-expressed BEX4. | 29660335 |
| 2017-12-23 10:23:00 | Study provides evidence that BEX4 functions as tumor suppressor by inhibiting proliferation and growth of oral squamous cell carcinoma (OSCC). Decreased BEX4 contributes to the increased proliferative propensity of OSCC. | 27297407 |
| 2017-10-14 11:28:00 | BEX4 overexpression causes an imbalance between TUB acetylation and deacetylation by SIRT2 inhibition and induces oncogenic aneuploidy transformation. | 27512957 |
| Type | IDs |
|---|---|
| Synonymous | BEXL1 |
| Gene |
UniProtKB-ID:
BEX4_HUMAN
UniprotKB:
Q9NWD9
UniParc:
UPI0000038D5E
EMBL:
AY833563,
AL035494,
AK000959
Ensembl:
ENSG00000102409
KO:
hsa:56271
|
| Nucleutide sequences |
EMBL-CDS:
AAX40681.1,
BAA91443.1
Ensembl_TRS:
ENST00000372691,
ENST00000372695
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361780,
ENSP00000361776
RefSeq:
NP_001073894.1,
NP_001121160.1
|
| Others |
UniRef100:
UniRef100_Q9NWD9
UniRef90:
UniRef90_Q9NWD9
UniRef50:
UniRef50_Q9NWD9
UniGene:
Hs.184736
CCDS:
CCDS35355.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33217815 |
Medicine (Baltimore) Chenhong Zhu , Deshuang Xiao |
2020-11-20 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30367032 |
Oncogenic potential of BEX4 is conferred by Polo-like kinase 1-mediated phosphorylation. Exp. Mol. Med. Jin-Kwan Lee , Geun-Hyoung Ha , Hyun-Soo Kim , Chang-Woo Lee |
2018-10-22 | - |
| 29660335 |
mTOR up-regulation of BEX4 promotes lung adenocarcinoma cell proliferation by potentiating OCT4. Biochem. Biophys. Res. Commun. Ziran Zhao , Jiagen Li , Fengwei Tan , Shugeng Gao , Jie He |
2018-06-02 | - |
| 27512957 |
Oncogenic microtubule hyperacetylation through BEX4-mediated sirtuin 2 inhibition. Cell Death Dis Jin-Kwan Lee , Janet Lee , Heounjeong Go , Chang Geun Lee , Suhyeon Kim , Hyun-Soo Kim , Hyeseong Cho , Kyeong Sook Choi , Geun-Hyoung Ha , Chang-Woo Lee |
2016-08-11 | - |
| 27297407 |
J. Exp. Clin. Cancer Res. Wei Gao , John Zeng-Hong Li , Si-Qi Chen , Chiao-Yun Chu , Jimmy Yu-Wai Chan , Thian-Sze Wong |
2016-06-13 | - |
| 26465331 |
PLoS One Julianne H Grose , Kelsey Langston , Xiaohui Wang , Shayne Squires , Soumyajit Banerjee Mustafi , Whitney Hayes , Jonathan Neubert , Susan K Fischer , Matthew Fasano , Gina Moore Saunders , Qiang Dai , Elisabeth Christians , E Douglas Lewandowski , Peipei Ping , Ivor J Benjamin |
2015-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 15958283 |
Characterization of the Bex gene family in humans, mice, and rats. Gene Enrique Alvarez , Wenbo Zhou , Samir E Witta , Curt R Freed |
2005-08-29 |
Bex2,
Ngfrap1,
Bex1,
Bex6,
Bex4,
Bex3,
Bex2,
Bex4,
Bex1,
BEX3,
BEX5,
BEX1,
BEX4,
BEX2
|
| 15772651 |
The DNA sequence of the human X chromosome. Nature Mark T Ross , Darren V Grafham , Alison J Coffey , Steven Scherer , Kirsten McLay , Donna Muzny , Matthias Platzer , Gareth R Howell , Christine Burrows , Christine P Bird , Adam Frankish , Frances L Lovell , Kevin L Howe , Jennifer L Ashurst , Robert S Fulton , Ralf Sudbrak , Gaiping Wen , Matthew C Jones , Matthew E Hurles , T Daniel Andrews , Carol E Scott , Stephen Searle , Juliane Ramser , Adam Whittaker , Rebecca Deadman , Nigel P Carter , Sarah E Hunt , Rui Chen , Andrew Cree , Preethi Gunaratne , Paul Havlak , Anne Hodgson , Michael L Metzker , Stephen Richards , Graham Scott , David Steffen , Erica Sodergren , David A Wheeler , Kim C Worley , Rachael Ainscough , Kerrie D Ambrose , M Ali Ansari-Lari , Swaroop Aradhya , Robert I S Ashwell , Anne K Babbage , Claire L Bagguley , Andrea Ballabio , Ruby Banerjee , Gary E Barker , Karen F Barlow , Ian P Barrett , Karen N Bates , David M Beare , Helen Beasley , Oliver Beasley , Alfred Beck , Graeme Bethel , Karin Blechschmidt , Nicola Brady , Sarah Bray-Allen , Anne M Bridgeman , Andrew J Brown , Mary J Brown , David Bonnin , Elspeth A Bruford , Christian Buhay , Paula Burch , Deborah Burford , Joanne Burgess , Wayne Burrill , John Burton , Jackie M Bye , Carol Carder , Laura Carrel , Joseph Chako , Joanne C Chapman , Dean Chavez , Ellson Chen , Guan Chen , Yuan Chen , Zhijian Chen , Craig Chinault , Alfredo Ciccodicola , Sue Y Clark , Graham Clarke , Chris M Clee , Sheila Clegg , Kerstin Clerc-Blankenburg , Karen Clifford , Vicky Cobley , Charlotte G Cole , Jen S Conquer , Nicole Corby , Richard E Connor , Robert David , Joy Davies , Clay Davis , John Davis , Oliver Delgado , Denise Deshazo , Pawandeep Dhami , Yan Ding , Huyen Dinh , Steve Dodsworth , Heather Draper , Shannon Dugan-Rocha , Andrew Dunham , Matthew Dunn , K James Durbin , Ireena Dutta , Tamsin Eades , Matthew Ellwood , Alexandra Emery-Cohen , Helen Errington , Kathryn L Evans , Louisa Faulkner , Fiona Francis , John Frankland , Audrey E Fraser , Petra Galgoczy , James Gilbert , Rachel Gill , Gernot Glöckner , Simon G Gregory , Susan Gribble , Coline Griffiths , Russell Grocock , Yanghong Gu , Rhian Gwilliam , Cerissa Hamilton , Elizabeth A Hart , Alicia Hawes , Paul D Heath , Katja Heitmann , Steffen Hennig , Judith Hernandez , Bernd Hinzmann , Sarah Ho , Michael Hoffs , Phillip J Howden , Elizabeth J Huckle , Jennifer Hume , Paul J Hunt , Adrienne R Hunt , Judith Isherwood , Leni Jacob , David Johnson , Sally Jones , Pieter J de Jong , Shirin S Joseph , Stephen Keenan , Susan Kelly , Joanne K Kershaw , Ziad Khan , Petra Kioschis , Sven Klages , Andrew J Knights , Anna Kosiura , Christie Kovar-Smith , Gavin K Laird , Cordelia Langford , Stephanie Lawlor , Margaret Leversha , Lora Lewis , Wen Liu , Christine Lloyd , David M Lloyd , Hermela Loulseged , Jane E Loveland , Jamieson D Lovell , Ryan Lozado , Jing Lu , Rachael Lyne , Jie Ma , Manjula Maheshwari , Lucy H Matthews , Jennifer McDowall , Stuart McLaren , Amanda McMurray , Patrick Meidl , Thomas Meitinger , Sarah Milne , George Miner , Shailesh L Mistry , Margaret Morgan , Sidney Morris , Ines Müller , James C Mullikin , Ngoc Nguyen , Gabriele Nordsiek , Gerald Nyakatura , Christopher N O'Dell , Geoffery Okwuonu , Sophie Palmer , Richard Pandian , David Parker , Julia Parrish , Shiran Pasternak , Dina Patel , Alex V Pearce , Danita M Pearson , Sarah E Pelan , Lesette Perez , Keith M Porter , Yvonne Ramsey , Kathrin Reichwald , Susan Rhodes , Kerry A Ridler , David Schlessinger , Mary G Schueler , Harminder K Sehra , Charles Shaw-Smith , Hua Shen , Elizabeth M Sheridan , Ratna Shownkeen , Carl D Skuce , Michelle L Smith , Elizabeth C Sotheran , Helen E Steingruber , Charles A Steward , Roy Storey , R Mark Swann , David Swarbreck , Paul E Tabor , Stefan Taudien , Tineace Taylor , Brian Teague , Karen Thomas , Andrea Thorpe , Kirsten Timms , Alan Tracey , Steve Trevanion , Anthony C Tromans , Michele d'Urso , Daniel Verduzco , Donna Villasana , Lenee Waldron , Melanie Wall , Qiaoyan Wang , James Warren , Georgina L Warry , Xuehong Wei , Anthony West , Siobhan L Whitehead , Mathew N Whiteley , Jane E Wilkinson , David L Willey , Gabrielle Williams , Leanne Williams , Angela Williamson , Helen Williamson , Laurens Wilming , Rebecca L Woodmansey , Paul W Wray , Jennifer Yen , Jingkun Zhang , Jianling Zhou , Huda Zoghbi , Sara Zorilla , David Buck , Richard Reinhardt , Annemarie Poustka , André Rosenthal , Hans Lehrach , Alfons Meindl , Patrick J Minx , Ladeana W Hillier , Huntington F Willard , Richard K Wilson , Robert H Waterston , Catherine M Rice , Mark Vaudin , Alan Coulson , David L Nelson , George Weinstock , John E Sulston , Richard Durbin , Tim Hubbard , Richard A Gibbs , Stephan Beck , Jane Rogers , David R Bentley |
2005-03-17 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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|---|---|---|
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